A-03 France Mentré
Pharmacometrics to support clinical investigation during COVID-19 pandemics
Thursday 13:10-13:55 |
A-03 Jeremie Guedj
Pharmacometrics to support clinical investigation during COVID-19 pandemics : a viral dynamics perspective
Thursday 13:10-13:55 |
A-04 Thorsten Lehr
Modeling and Simulation of SARS-CoV-2 Infections, Hospitalizations and Outcome in Germany
Thursday 13:55-14:40 |
A-05
Social break
Thursday 14:40-15:40 |
A-08 Nadege Neant
Modeling SARS-CoV-2 viral kinetics in hospitalized patients
Thursday 15:45-16:05 |
A-09 Mélanie Prague
Using population approach to model COVID-19 epidemics in France: estimating the burden of SARS-Cov-2 and the effects of non-pharmaceutical interventions.
Thursday 16:05-16:25 |
A-10 Seth Robey
Predictive Primates: Enabling Rapid Go/No-Go Decisions on COVID-19 Vaccine Candidates with a Predictive, Translational MBMA and Clinical Immunogenicity Data
Thursday 16:25-16:45 |
A-11
Break
Thursday 16:45-16:55 |
A-13 Andrew Hooker
Tutorial on survival analysis and its application to the assessment of competing risks in clinical data analysis.
Thursday 16:55-17:10 |
A-14 Joachim Grevel
Tutorial on application of survival analysis to the assessment of multiple state models in clinical data analysis.
Thursday 17:10-17:40 |
A-15
Day End
Thursday 17:40 |
B-01
Poster Session I
Friday 12:00-13:00 |
B-03 Rob van Wijk
Translational quantitative systems pharmacology; crossing borders between experimental and computational drug development using zebrafish as model organism
Friday 13:00-13:25 |
B-04 Eleni Karatza
Machine-Learning for cancer treatment: Guided covariate selection for TTE models developed from real world data with a small number of patients
Friday 13:25-13:50 |
B-05 Vincent Chang
In silico assessment of adaptive trial design for TB regimen development
Friday 13:50-14:15 |
B-08
Social Break
Friday 14:30-15:30 |
B-10 Linda Aulin
Model-based design of innovative treatment strategies to suppress antimicrobial resistance using collateral sensitivity
Friday 15:30-15:55 |
B-11 Marion Kerioui
Bayesian modelling of individual lesions dynamics and survival to characterize response to immunotherapy cancer treatments
Friday 15:55-16:20 |
B-12 Anna Mc Laughlin
Population quantitative systems pharmacology model of distinct CAR-T cell phenotypes and CD19-specific metabolic tumour volume reveals sources of high pharmacokinetic variability and overall survival
Friday 16:20-16:45 |
B-14
Break
Friday 16:50-17:00 |
B-16 Alexander Janssen
The Neural Mixed Effects algorithm: leveraging machine learning for pharmacokinetic modelling
Friday 17:00-17:20 |
B-17 James Lu
Deep Learning for PK/PD and Disease Progression Time-Course Predictions using Neural-ODE
Friday 17:20-17:40 |
B-18
Day End
Friday 17:40 |
C-01
Poster Session II
Monday 12:00-13:00 |
C-03 Vladimir Dragalin
Adaptive trial designs: opportunities and challenges
Monday 13:00-13:45 |
C-04
Break
Monday 13:45-13:50 |
C-07 Anyue Yin
Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance
Monday 14:00-14:20 |
C-08 Sreenath M Krishnan
Multistate model for pharmacometric analyses of overall survival in anticancer treatments
Monday 14:20-14:40 |
C-09 René Bruno
Operating characteristics of tumor growth inhibition-overall survival models to support early Phase Ib decisions: An evaluation in first-line metastatic non-small cell lung cancer patients treated with atezolizumab plus chemotherapy based on the Phase III study IMpower150
Monday 14:40-15:00 |
C-10
Social Break
Monday 15:00-16:00 |
C-12 Verena Gotta
Personalizing hemodialysis (HD) treatment in pediatric patients with end-stage renal disease (ESRD) – application and integration of quantitative pharmacology with machine learning
Monday 16:00-16:20 |
C-13 Jasmine Hughes
A hybrid machine learning/pharmacokinetic approach improves predictive performance in model-informed precision dosing
Monday 16:20-16:40 |
C-14 Diego Vera-Yunca
Semi-mechanistic modeling of tumor size and overall survival including machine learning-derived tumor heterogeneity
Monday 16:40-17:00 |
C-15
Break
Monday 17:00-17:05 |
C-17 Nicolás Marco Ariño
The broad use of pharmacometrics in patient care: the case of blood transfusion and perioperative management
Monday 17:05-17:25 |
C-18 Estelle Yau
A systematic framework for the incorporation of preclinical species data into physiologically-based pharmacokinetic models using a middle-out approach to improve the translation of drug distribution in humans
Monday 17:25-17:45 |
C-19
Day End
Monday 17:45 |
D-01
Poster Session III
Tuesday 12:00-13:00 |
D-03 Carolina Llanos-Paez
Use of item-based non-linear mixed effects model to improve confidence in Phase III clinical trial decision-making
Tuesday 13:00-13:20 |
D-04 Iris Minichmayr
Beyond disease progression – Item response theory modelling to gain structural insights into disease facets underlying clinical score assessments
Tuesday 13:20-13:40 |
D-05 Alexandra Lavalley-Morelle
Individual dynamic predictions in joint analysis for nonlinear marker evolution and competing risk data: application on patients admitted in Intensive Care Unit for sepsis
Tuesday 13:40-14:00 |
D-06
Break
Tuesday 14:00-14:20 |
D-09 Zoe Kane
Development of a neonatal plasma and cerebrospinal fluid (CSF) population PK model for fosfomycin.
Tuesday 14:30-14:50 |
D-10 David Busse
Body composition and drug exposure in adipose tissue are key for antibiotic dose-individualisation in obese individuals
Tuesday 14:50-15:10 |
D-11 Jérémy Seurat
Combination of in vivo phage therapy data with in silico model highlights key parameters for treatment efficacy
Tuesday 15:10-15:30 |
D-12
Social Break
Tuesday 15:30-16:15 |
D-14 Roeland Wasmann
A pharmacometric approach to optimise Fixed-Dose Combinations of Rifampicin, Isoniazid, and Pyrazinamide for children with tuberculosis
Tuesday 16:15-17:35 |
D-15 Marie Alexandre
Dynamics of the humoral immune response to a two-dose heterologous vaccine regimen against Ebola virus.
Tuesday 16:35-16:55 |
D-16 João Abrantes
Model-informed development of RG6102, an amyloid-targeting investigational drug with enhanced brain penetration properties
Tuesday 16:55-17:15 |
