I-35 Núria Buil Bruna Population PK/PD modelling of the biomarker and progression free survival effects of Lanreotide Autogel in patients with non-functioning gastroenteropancreatic neuroendocrine tumors Wednesday 10:45-12:15 |
I-39 Tim Cardilin Modelling and Analysis of Tumor Growth Inhibition for Combination Therapy using Tumor Static Concentration Curves Wednesday 10:45-12:15 |
I-40 Letizia Carrara Modelling the effect of Sunitinib given alone and in combination with CPT-11 on the tumor growth in xenografted mice Wednesday 10:45-12:15 |
I-45 Christophe Chassagnole Modelling Synergistic Immunotherapy Combinations with Virtual Tumour Wednesday 10:45-12:15 |
I-57 Laurent Claret A comparison of two stage and joint tumor growth inhibition-progression free survival modeling approach to simulate clinical outcome in oncology Wednesday 10:45-12:15 |
I-61 Ana Margarita Contreras Sandoval Towards a platform PK/PD model for an anti-PD-L1 monoclonal antibody through a preclinical syngeneic melanoma mouse model Wednesday 10:45-12:15 |
I-65 Camila De Almeida PKPD-efficacy modelling of AZD9496, a novel oral selective estrogen receptor downregulator Wednesday 10:45-12:15 |
II-23 Ahmed Suleiman A Modeling and Simulation Framework Characterizing the Time Courses of Adverse Events in Non-Small Cell Lung Cancer Patients Treated with Erlotinib Wednesday 15:15-16:40 |
II-33 Hoai-Thu Thai Joint modeling of longitudinal tumor burden and time-to-event data to predict survival: application to aflibercept in second line metastatic colorectal cancer Wednesday 15:15-16:40 |
II-36 Melanie Titze PK/PD modeling of biomarker modulation and tumor growth inhibition by BI 893923, a novel IGF-1 receptor inhibitor Wednesday 15:15-16:40 |
II-38 Mira Tout The impact of initial metabolic tumor volume on rituximab pharmacokinetics and clinical response in patients with diffuse large B-cell lymphoma Wednesday 15:15-16:40 |
II-51 Johan Wallin Overall survival and change in tumor size in squamous NSCLC in relation to Necitumumab exposure Wednesday 15:15-16:40 |
II-60 Paul Westwood Population pharmacokinetic meta-analysis of ramucirumab in cancer patients Wednesday 15:15-16:40 |
II-71 Chiara Zecchin Modelling change in tumour size, survival and new lesions appearance in patients with ovarian cancer treated with carboplatin monotherapy or in combination with gemcitabine Wednesday 15:15-16:40 |
III-01 Kristin Dickschen PBPK modeling to guide experimental design in preclinical and clinical development Thursday 10:20-11:45 |
III-08 Miro Eigenmann Modeling of acquired resistance under TKI treatment Thursday 10:20-11:45 |
III-15 Achim Fritsch PK/PD Modeling of Sunitinib in Patients with Metastatic Colorectal and Renal Cell Cancer Thursday 10:20-11:45 |
III-18 María García-Cremades Modelling tumour growth and survival of patients with pancreatic cancer receiving Gemcitabine Thursday 10:20-11:45 |
III-22 Ekaterina Gibiansky Comparison of Population Pharmacokinetics and Exposure-Response Relationships of Intravenous Rituximab and Subcutaneous Rituxumab in Patients with Chronic Lymphocytic Leukemia Thursday 10:20-11:45 |
III-31 Beatriz Guglieri-Lopez A tumour growth inhibition model based on serum M-protein levels in patients with multiple myeloma treated by lenalidomide. Thursday 10:20-11:45 |
III-35 Kelong Han Tumor Growth Inhibition Modeling of Onartuzumab in Combination with Erlotinib Does Not Suggest Dose Intensification Would Improve Outcome in Patients with 2nd and 3rd Line Non-small Cell Lung Cancer Thursday 10:20-11:45 |
III-38 Andrea Henrich External evaluation of a PK/PD model describing the time course of paclitaxel and neutropenia in patients with advanced non-small cell lung cancer Thursday 10:20-11:45 |
III-61 Matts Kågedal Binning of exposures in survival analysis for oncology – A simulation study Thursday 10:20-11:45 |
III-66 Lena Klopp-Schulze In silico simulation study: A comparison of two population pharmacokinetic models of tamoxifen and its major metabolite endoxifen Thursday 10:20-11:45 |
III-75 Olivia le Saux Development and validation of a model of PSA kinetics predicting prostate cancer aggressiveness during screening Thursday 10:20-11:45 |
III-76 SeungHwan Lee A population pharmacokinetic analysis of CKD-516 in patients with advanced solid tumor Thursday 10:20-11:45 |
IV-33 Ida Neldemo Assessment of the Predictive Properties of C-Reactive Protein and Interleukin 6 on Febrile Neutropenia Thursday 15:20-16:40 |
IV-43 Aziz Ouerdani Effects of Bevacizumab and Everolimus for the treatment of Vestibular Schwannomas in patients with Neurofibromatosis Type 2 Thursday 15:20-16:40 |
IV-53 Alejandro Pérez-Pitarch Growing evidence supporting therapeutic drug monitoring of erlotinib in non-small-cell lung cancer patients: a time-to-progression model. Thursday 15:20-16:40 |
IV-54 Carlos Perez-Ruixo Platelets dynamics in peritoneal carcinomatosis patients treated with cytoreductive surgery and hyperthermic intraperitoneal oxaliplatin Thursday 15:20-16:40 |
IV-55 Aurelie Petain Inter-species comparison of semi-physiological pre-clinical PK/PD models to better predict the time course of myelosuppression in human: application to a novel vectorized epipodophyllotoxin (F14512) Thursday 15:20-16:40 |
IV-57 Philippe Pierrillas Improvement of parameter estimations in tumor growth inhibition models on xenografted animals: a novel method to handle the interval-censoring caused by experimental measurement on smaller tumor sizes Thursday 15:20-16:40 |
IV-58 Maiara Pigatto PK/PD modeling of tumor growth inhibition after etoposide administration in vitro and to tumor-bearing rats Thursday 15:20-16:40 |
IV-59 Venkatesh Pilla Reddy Modelling and simulation of concentration-depth-time profiles in the urinary bladder wall following intravesical delivery Thursday 15:20-16:40 |
IV-75 Maria Luisa Sardu Xenograft experiments: assessing consistency between a drug-driven and a biomarker-driven tumor growth inhibition model Thursday 15:20-16:40 |