Thursday 16 October, 2025
PDF of poster Introduction: A phase II dose-ranging study is planned for a drug in clinical development. The pharmacokinetics (PK)…
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Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine
Thursday 16 October, 2025
Zipped PDF of poster Objectives: The stimulant effect of caffeine, as an additive in legal diacetylmorphine (heroin) preparations for study…
Read morePopulation Pharmacokinetics and Response of ICL670 a Novel Oral Iron Chelator in Beta-Thalassaemia Patients
Thursday 16 October, 2025
PDF of poster Objectives: To develop a population pharmacokinetic model for ICL670 and the iron-complex Fe-[ICL670]2. Methods: A population approach…
Read moreAge-related effects on nelfinavir – M8 pharmacokinetics – A population study in 182 children
Thursday 16 October, 2025
PDF of poster Objective: As a relationship between nelfinavir antiretroviral efficacy and plasma concentrations has been previously established, the large…
Read moreGeneralisation of the SAEM algorithm to nonlinear mixed effects model defined by differential equations : application to HIV viral dynamic models
Thursday 16 October, 2025
PDF of poster Objectives: We consider parametric mixed models whose regression functions are solution of an ordinary differential equation (ODE)….
Read morePopulation Pharmacokinetics of Teicoplanin in Outpatient Home Parenteral Antibiotic Therapy (OHPAT)
Thursday 16 October, 2025
PDF of poster Introduction. The Outpatient Home Parenteral Antibiotic Therapy (OHPAT) service has been developed to manage infections in patients…
Read morePopulation PK Analysis in Sparse Data and Flexible Sampling Time Conditions
Thursday 16 October, 2025
PDF of poster Objective: Characterize the pharmacokinetics including effects of covariates of a tested drug, based on a phase II…
Read moreA Bayesian design and analysis for dose-response using informative prior information
Thursday 16 October, 2025
PDF of poster Objectives: We wish to optimise the design of a dose-response trial and obtain good estimates of relative…
Read morePopulation pharmacokinetics of the new antiepileptic drug lacosamide in healthy subjects with different age and gender
Thursday 16 October, 2025
PDF of poster Objectives: Characterization of population pharmacokinetics of the new antiepileptic drug lacosamide in young healthy male and elderly…
Read morePopulation pharmacokinetics of S-mephenytoin and its metabolites S-nirvanol and S-4-hydroxymephenytoin in CYP2C19 poor, intermediate and extensive metabolizers.
Thursday 16 October, 2025
PDF of poster Objectives: The aim of this study was to develop a model to describe the pharmacokinetics of S-mephenytoin,…
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