Thursday 16 October, 2025
PDF of poster Introduction: Delta9-tetrahydrocannabinol (THC) is the most well known pharmacologically active cannabinoid, acting as a CB1 and CB2…
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Non-Adherence to Prescribed Therapy is a Major Obstacle for Population PK/PD Studies
Thursday 16 October, 2025
PDF of poster Background: The extent of non-adherence to prescribed therapy in ambulatory patients is too often overlooked and ignored…
Read morePredicting recovery progression in acute stroke using the Barthel Index
Thursday 16 October, 2025
PDF of poster Objectives: This study was designed to refine analytical techniques for describing and predicting disease progression in acute…
Read moreA population pharmacokinetic-enzyme model for rifampicin autoinduction and bimodal absorption in pulmonary tuberculosis patients
Thursday 16 October, 2025
PDF of poster Objectives: This study was designed to describe the pharmacokinetics of rifampicin in South African pulmonary tuberculosis patients…
Read moreRobust Population Pharmacokinetic Experiment Design
Thursday 16 October, 2025
Objectives: The population approach to estimating mixed effects model parameters of interest in pharmacokinetic (PK) studies has been demonstrated to…
Read moreA Population PK Model for Recombinant Factor XIII in Congenitally Deficient Subjects
Thursday 16 October, 2025
Purpose: To develop a population pharmacokinetic model to describe the fate of recombinant FXIII-A2 (rA2) subunit administered to patients congenitally…
Read moreApplication of Population Pharmacokinetic Analysis for Quantification of in vivo Binding Properties in the Rat Brain by Positron Emission Tomography
Thursday 16 October, 2025
PDF of poster Objectives: Changes in GABAA receptor density and affinity play an important role in many forms of epilepsy….
Read morePopulation Pharmacokinetic/Pharmacodynamic Analysis of Different Subunit Selective GABAergic Ligands in an Animal Model of Epilepsy
Thursday 16 October, 2025
PDF of poster Objectives: Changes in GABAA-receptor functionality play an important role in many forms of epilepsy. One of the…
Read moreEffect of Uncertainty About Population Parameters on Pharmacodynamics-Based Prediction of Clinical Trial Power – A Method for Sensitivity Analysis
Thursday 16 October, 2025
PDF of poster In clinical trial simulation (CTS), uncertainty about population parameters determining the shape of the simulation model will…
Read moreEvaluation of an enterohepatic circulation model: predicting the influence of cholestyramine on the pharmacokinetics of meloxicam
Thursday 16 October, 2025
PDF of poster Objectives & Background: Concentration-time profiles of drugs undergoing enterohepatic circulation (EHC) are often associated with multiple peak…
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