PDF of poster Background and Objectives: Depression is one of the most common and treatable of mental illness. In any…
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Structural identifiability analysis of some semi-physiologically based and whole body physiologically based (WBPBPK) pharmacokinetic models.
PDF of poster Objectives: It is essential to establish the importance and raise the awareness of structural identifiability analysis [1]…
Read morePopulation pharmacokinetics of tenofovir in HIV-infected patients taking highly active antiretroviral therapy.
Objectives: This study was performed to investigate the influence of renal function on tenofovir pharmacokinetics in HIV-infected adults with creatinine…
Read morePopulation pharmacokinetics of lopinavir in HIV-infected adults receiving lopinavir/ritonavir
Objectives: Lopinavir (LPV) is an inhibitor of the protease of the human immunodeficiency virus (HIV). In order to exploit its…
Read moreDeterminants of the pharmacokinetics of methotrexate and its metabolite 7-hydroxy-methotrexate following high-dose infusional methotrexate
PDF of poster Objectives: The identification of methotrexate (MTX) and 7-hydroxy-methotrexate (7-OH-MTX) pharmacokinetics and its determinants is very useful in…
Read morePharmacokinetics modelling and anti-Xa level simulation of enoxaparin used for venous thromboembolism prophylaxis after orthopaedic surgery
PDF of poster Introduction: The use of enoxaparin to prevent venous thromboembolism after orthopaedic surgery at a fixed dose (40…
Read morePopulation pharmacokinetics of enoxaparin used for thromboembolism prophylaxis after total hip replacement
PDF of poster Introduction: Enoxaparin is usually given for venous thromboembolism prophylaxis in orthopaedic surgery, at a fixed dose of…
Read morePrediction of Clearance in Children Using a Combined Physiology-based and Enzyme Ontogeny Approach
PDF of poster Objective: Clearance is a critical pharmacokinetic concept for scaling dosage, understanding the risks of drug-drug interactions and…
Read morePredicting pharmacokinetics in children using PK-Sim®
PDF of poster Objective: Approaches that are able to predict potential differences in the pharmacokinetic behavior of a compound in…
Read moreDesigning Sparse-Sampling Schemes for Population PK Study of a Highly Variable Drug.
PDF of poster Objective: Design a sparse sampling scheme for a population PK component of an efficacy trial of an…
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