The former investigation made the modeling of pharmacokinetic observations from 16 samples/patient possible. What are the parameter mean values if…
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Population of Vancomycine with Continuous Infusion Administered in Neutropenic Patients Modeling on NPEM2-NONMEM-P-PHARM
Analysing concentration of vancomycine individually showed that pharmacokinetic parameters show a marked inter-and intra-individual variability and more particulary on the…
Read moreThe Relationship Of Phenytoin Concentrations To Gingival Hyperplasia
The aims of this study were to ascertain the prevalence and severity of phenytoin-induced gingival hyperplasia in patients who attend…
Read morePopulation Pharmacokinetics Of Proguanil In Patients With Acute P Falciparum Malaria After Combined Therapy With Atovaquone
The pharmacokinetics of proguanil were evaluated in patients with acute P falciparum malaria receiving concomitantly proguanil and atovaquone from 6…
Read moreProbability Statements About Predicted Kinetic/Dynamic Profiles In Population Analyses
A__ contains F__ which has a highly selective activity against ticks. Cows were treated with 2.5 mg/kg A__ at 2…
Read moreMP2 (V 2.0) A Windows® Application For Population Pharmacokinetics
This project is developed for population pharmacokinetic modeling of experimental data. The program is written in Pascal language and runs…
Read moreA Pharmacokinetic Model For Morphine Incorporating Acute Tolerance And M3G Interactions
This investigation was carried out to evaluate if and to what extent morphine-3-glucuronide (M3G) antagonise morphine antinociceptive effects or is…
Read morePopulation Pharmacokinetics Of Valsartan
Valsartan is one of a new class of anti-hypertensive agents, known as angiotensin II antagonists. Its pharmacokinetics and variability, both…
Read morePharmacokinetics Of Piritramide In Patients Undergoing Elective Surgery
Introduction: Piritramide, a synthetic opioid, is currently investigational drug in the United States. This study was designed to characterize the…
Read moreLiarozole Population Pharmacokinetics At The Steady State
Population analysis of liarozole pharmacokinetics was performed using the NONMEM approach. The database consisted in liarozole plasma concentration measurements obtained…
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