Thursday 16 October, 2025
PowerPoint of poster Background: The presence of a prolonged QT-interval has become an identifier for the risk of a unique…
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Model Based Insights to Lamotrigine for Pain Associated with Diabetic Peripheral Neuropathy
Thursday 16 October, 2025
PDF of poster Lamotrigine was studied for pain associated with diabetic peripheral neuropathy in replicate, randomized, double-blind, placebo (PBO) controlled,…
Read morePharmacokinetic/Pharmacodynamic Modelling of the Anticoagulant Activity of Warfarin
Thursday 16 October, 2025
PDF of poster Introduction: Racemic warfarin is the most widely prescribed anticoagulant drug for the prevention and treatment of tromboembolic…
Read morePharmacokinetics- guided targeting of mycophenolate mofetil (MMF) in combination renal transplantation treatment confirms the need for dose reduction
Thursday 16 October, 2025
PDF of poster Purpose To use a prospective population pharmacokinetic (PK) method, and Bayesian estimates of the AUC, to optimize…
Read morePopulation pharmacokinetics of lamotrigine in epileptic patients with data proceeding of therapeutic drug monitoring
Thursday 16 October, 2025
PDF of poster Population pharmacokinetics of lamotrigine in epileptic patients with data proceeding of therapeutic drug monitoring N. Rivas, D…
Read moreDevelopment and evaluation of a population pharmacokinetic model for cilobradine, an If channel blocker
Thursday 16 October, 2025
PDF of poster Objectives: The If channel blocker cilobradine belongs to a class of bradycardic agents selectively decreasing heart rate…
Read moreA mathematical model for paroxetine antidepressant effect time course and its interaction with pindolol
Thursday 16 October, 2025
PDF of poster Background: Although selective 5-HT reuptake inhibitors (SSRIs) block monoamine uptake within hours of administration, their full clinical…
Read morePrediction of drug-drug interactions and their associated variability in human populations: Application to erlotinib and its coadministration with ketoconazole and rifampicin
Thursday 16 October, 2025
PDF of poster Background: Drug–drug interactions (DDIs) mediated by cytochrome P450 enzymes are a potential cause of toxicity with co-medications….
Read moreThe effect of rufinamide concentration on the QT interval in healthy subjects treated during 18 days with multiple ascending doses: a population PKPD analysis.
Thursday 16 October, 2025
PDF of poster Objectives: A double-blind, placebo-controlled, ascending multiple dose study was performed to evaluate the cardiovascular safety, the tolerability,…
Read morePK-PD model compared with K-PD model to predict haematotoxicity induced by anticancer drugs.
Thursday 16 October, 2025
PDF of poster Introduction: Pharmacokinetic-pharmacodynamic (PK-PD) models are available to predict haematological toxicity induced by anticancer chemotherapy, but they need…
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