Poster: Drug/Disease modeling - Paediatrics

PPK analysis of Rouvastatin in Children and Adolescents (ages 6 to <18 years of age) with Familial Hypercholesterolemia to Support Regulatory Approval

Thursday 16 October, 2025

Objectives: To describe the pharmacokinetic properties of rosuvastatin in children ≥6 to < 18 years of age. Methods: A two-compartment population…

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Population pharmacokinetics of bumetanide in term newborn infants with seizures

Thursday 16 October, 2025

Objectives: Experimental data supported the use of bumetanide for the treatment of neonatal seizures due to hypoxic-ischaemic encephalopathy (HIE). The…

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Simultaneous pharmacokinetic modeling of gentamicin, tobramycin and vancomycin clearance from neonates to adults: towards a semi-physiological function for maturation in glomerular filtration.

Thursday 16 October, 2025

Objectives: Since glomerular filtration rate (GFR) is responsible for the elimination of a large number of water-soluble drugs [1], the…

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Population Pharmacokinetic Meta-Analysis of the Antiretroviral Agent Abacavir in HIV-Infected Children

Thursday 16 October, 2025

Objectives: Abacavir (ABC) is one of the recommended nucleoside reverse transcriptase inhibitor (NRTI) against human immunodeficiency virus (HIV); ABC is…

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