Thursday 16 October, 2025
Objectives: The aims of this study were to describe the pharmacokinetics of the cotrimoxazole (CTX : association of sulfamethoxazole (SMX) and…
Read morePoster: Drug/Disease modeling - Paediatrics
Amikacin in premature newborn: a new therapeutic proposal from a PopPK model
Thursday 16 October, 2025
Objectives: To develop a population pharmacokinetic model of amikacin in premature newborns babies. From the estimated population model, establish new therapeutic…
Read morePopulation pharmacokinetics of oxcarbazepine and its 10-monohydroxy derivative in epileptic children
Thursday 16 October, 2025
Objectives: Oxcarbazepine is a recent antiepileptic drug (AED) used in focal seizures in both children and adults. Its activity is mostly…
Read moreMaturation of Glomerular Filtration throughout the paediatric age-range; a comparison of different functions
Thursday 16 October, 2025
Objectives: Glomerular filtration (GF) has a key role in the renal elimination of many drugs. Establishing an accurate ontogeny function for…
Read moreOptimisation of weight-banded dosing regimens of amoxicillin in neonates and young infants with sepsis
Thursday 16 October, 2025
Objectives: To assess the feasibility of a simplified regimen for amoxicillin in pre-term and term infants (0 – 59 days)…
Read morePopulation Pharmacokinetics of Voriconazole in pediatric cancer patients – assessing new dosing strategies
Thursday 16 October, 2025
Objectives: In order to predict new dosing regimens to receive more sustainable trough concentrations in the supposed range of 1…
Read moreZika microcephaly cutoffs revisited: A study of Non-parametric methods in fetal growth
Thursday 16 October, 2025
Objectives: An observed increase in the number of cases of microcephaly in Brazil has been associated with exposure to the…
Read morePopulation pharmacokinetics of sufentanil after epidural and intravenous administration in children and infants
Thursday 16 October, 2025
Objectives: Sufentanil is a potent opioid widely used in anesthetic and intensive care management. Literature data describing pharmacokinetics of sufentanil…
Read moreBioequivalence of desmopressin in children: a population pharmacokinetic study
Thursday 16 October, 2025
Introduction: Off-label use of drugs in the pediatric population is widespread: 50-90% of drugs are not tested in children [1]. The…
Read morePopulation pharmacokinetics of F-ara-A after fludarabine administration in pediatric hematopoietic stem cell transplantation patients
Thursday 16 October, 2025
Objectives: Fludarabine, a prodrug that is dephosphorylated to F-ara-A [1], is used as a component of conditioning regimens of hematopoietic…
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