The Uppsala University pharmacometrics group develops and maintains several different open-source software packages.assemblerr – Construction of pharmacometric models by combining…
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Simcyp Simulator
Simcyp Simulator – a user-friendly IVIVE-PBPK platform and database for mechanistic modelling, simulation and prediction of drug absorption, tissue distribution,…
Read moreTDMx: A web-application for therapeutic drug monitoring enhanced by pharmacometrics
Background: Pharmacometric models have evolved as useful tools to quantify and explain pharmacokinetic (PK) variability between patients and to explore…
Read moreggPMX: re-imagine diagnostics plots
Introduction: ggPMX is an open-source R package freely available on CRAN. It builds on the R-package ggplot2 and provides a…
Read moreLiterate Programming Methods for Clinical M&S
Objectives: Develop an effective Literate Programming/Reproducible Research environment for Modeling and Simulation of clinical data that serves as a “back-end”…
Read moreSimBiology: A Graphical Environment for Population PK/PD
Objective: To demonstrate the capabilities of SimBiology® for pharmacokinetic/pharmacodynamic (PK/PD) modeling and analysis Background: SimBiology® is a graphical environment for pharmacokinetic/pharmacodynamic…
Read moreArtificial Intelligence/Machine Learning (AI/ML) SubSIG of SxP: A collaboration to advance Pharmacometrics using AI/ML methods.
Artificial Intelligence (AI) is a widely known field originated from computer science, including theory and development of computer systems to…
Read morePopED – An optimal experimental design software
PopED is an Optimal Experimental Design tool for Non-Linear Mixed Effect Models [1]. Key features of PopED include the ability…
Read morePK-Sim and MoBi for PBPK and Quantitative Systems Pharmacology Modeling and Simulation
The Bayer Computational Systems Biology Software Suite contains different software tools and has been designed using a modular concept to…
Read morePipeline Pilot – Data Integration, Analysis, and Reporting Platform
Workflow technology is being increasingly applied in research and development information to organise and analyse data. Pipeline Pilot is a…
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