Software Demonstration

Pharmpy: an open-source software package for pharmacometric modeling and scripting

Thursday 7 May, 2026

Pharmpy [1] is an open-source software package for pharmacometric modeling intended for scripting of pharmacometric workflows and automated model development….

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Extending the open source saemix package to multiple responses and complex models

Thursday 7 May, 2026

Introduction: Quantifying the sources of individual variability in drug concentrations through non-linear mixed effect models (NLMEM) has proven instrumental in…

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CYTOCON AND FIVEDB: FREELY ACCESSIBLE DATABASES FOR STREAMLINING QSP MODEL CALIBRATION AND VALIDATION

Thursday 7 May, 2026

Objectives: Quantitative Systems Pharmacology (QSP) model development requires extensive data for calibration and validation, yet sourcing these data from literature…

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Open source software from the Uppsala University Pharmacometrics group

Thursday 7 May, 2026

The Uppsala University pharmacometrics group develops and maintains several different open-source software packages. ncappc – Performs traditional non-compartmental analysis (NCA)…

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Executing >100,000 Model Fits: Scalable and Reproducible Pharmacometric Workflows Using NLME/RsNLME

Thursday 7 May, 2026

Objectives Pharmacometric analyses increasingly rely on complex nonlinear mixed-effects (NLME) modeling, large-scale simulations, and simulation-based inference to support study design,…

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rock and roll – Deliverables driven by standardized data specifications

Thursday 7 May, 2026

Objectives: The process of creating analysis-ready data deliverables is a vital part of any pharmacometrics workflow, but is prone to…

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OpenPMX software for simulation and estimation in pharmacometrics

Thursday 7 May, 2026

Introduction: Nonlinear mixed-effects models are fundamental to pharmacometrics, and the first-order conditional estimation with interaction (FOCE-I) method implemented in NONMEM[1]…

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nmbench: An Integrated Text-Editor–Based Environment for NONMEM Population Modeling and Simulation

Thursday 7 May, 2026

Objectives: NONMEM remains the gold standard for population pharmacokinetic/pharmacodynamic (PK/PD) modeling and simulation. Despite its analytical robustness, routine modeling workflows…

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Automatic digitization of time series plots from published sources with EVA application

Thursday 7 May, 2026

Objectives: Extraction of quantitative data from published figures is a necessary but dreary and severely time-consuming step that follows systematic…

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Artificial Intelligence/Machine Learning (AI/ML) SubSIG of SxP: A collaboration to advance Pharmacometrics using AI/ML methods

Thursday 7 May, 2026

The Artificial Intelligence and Machine Learning Sub Special Interest Group (AI/ML SubSIG) of the ISoP–ASA Statistics and Pharmacometrics (SxP) SIG…

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