Thursday 16 October, 2025
Objectives: Monoclonal antibodies (mAbs) have been modified to promote binding affinity, half-life in circulation and effectiveness towards targets, especially in…
Read morePoster: Methodology - Other topics
Quantitative approaches of time-varying weight gain effects of antipsychotic drugs for Schizophrenia by model based meta-analysis.
Thursday 16 October, 2025
Objectives: Despite weight gain is one of the most important adverse drug effect(ADR) of antipsychotics[1], the quantitative approach was restricted…
Read moreConstruction of model-based PK-PD software platform using R package considering compatibility of nlme structured model
Thursday 16 October, 2025
Objectives: Nowadays, with overall improvement in medical standards, demand of individualized pharmaceutical intervention is on growing. On the other hand,…
Read moreGeneration of a virtual population for a multi-strain model of natural and vaccinal immunization against influenza
Thursday 16 October, 2025
Objectives: The generation of a Virtual Population (VP) is the one of the last steps of a QSP model calibration…
Read moreComparing Multiple Virtual Population Generation Approaches using as a base, a QSP Model of Rheumatoid Arthritis.
Thursday 16 October, 2025
Introduction: Virtual cohort and Virtual Population (VPop) generation are important outputs in the QSP process that attempt to capture the statistics…
Read moreComparing the objective function value in NONMEM is valid for model selection when fixing THETA or OMEGA but not when fixing ETAs
Thursday 16 October, 2025
Introduction: In population PKPD modeling a common aim is to use models to make predictions on quantities of interest of…
Read moreFacilitating structural population PK model building for pharmacometricians and beyond
Thursday 16 October, 2025
Introduction: Population pharmacokinetic (PK) analyses not only require a pharmacometric understanding but also a decent knowledge of the software used…
Read moreA meta-analysis of prevalence and incidence of diabetic peripheral neuropathy in Asia
Thursday 16 October, 2025
Introduction: Diabetes mellitus (DM) is a chronic metabolic disorder which contributes to many healthcare related problems globally and is more…
Read moreEvaluation of treatment effects in genetic ataxias using SARA score modelling: comparison of multiple trial designs by a large trial simulation framework
Thursday 16 October, 2025
Objectives: Genetic cerebellar ataxias are progressive rare neurological diseases affecting the cerebellum, often with multi-systemic damage to other neurological systems,…
Read moremastering upset plots: a comprehensive tutorial for effective data visualization in pharmacometrics and drug development
Thursday 16 October, 2025
Introduction/Objectives: In the realm of data analysis, the examination of variable intersections holds paramount importance as it often unveils crucial…
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