Thursday 16 October, 2025
Objectives: Linezolid is the first antibiotic of a new class of antimicrobial agents, the oxazolidinones, to be approved for clinical…
Read morePoster: Applications- Anti-infectives
Pharmacokinetic/Pharmacodynamic Modeling of Adaptive Resistance of Gentamicin
Thursday 16 October, 2025
Objectives: Adaptive resistance is a pharmacodynamic process that is characterized by a reversible refractoriness to the bactericidal action of an…
Read morePredictions of Dosing Schedules of Gentamicin in Neonates Based on a Pharmacokinetic/Pharmacodynamic Model Considering Adaptive Resistance
Thursday 16 October, 2025
Objectives: Adaptive resistance, a pharmacodynamic process of aminoglycosides, is a reversible refractoriness to the bactericidal action. It is developing during…
Read morePopulation pharmacokinetics of imipenem bone concentrations in pigs
Thursday 16 October, 2025
Objectives: Imipenem (IPM) is a broad-spectrum β-lactam antibiotic frequently used in intensive care units to treat nosocomial infections and BGN…
Read morePharmacokinetic/Pharmacodynamic (PK/PD) Modeling for Integrase Inhibitors with a Simple Viral Dynamic Model
Thursday 16 October, 2025
Objectives: S/GSK1349572, S/GSK1265744 and S/GSK364735 are potent, low nanomolar inhibitors of both recombinant HIV integrase and HIV replication in cell…
Read moreA Semi-Mechanistic pharmacokinetic enzyme model for the characterisation of rifampicin pharmacokinetics in South African pulmonary tuberculosis infected adults
Thursday 16 October, 2025
Objectives: Rifampicin, together with other first line regimen drugs, is used to treat drug sensitive Mycobacterium Tuberculosis. Rifampicin is known…
Read moreMechanistic pharmacokinetic enzyme model for the characterisation of rifampicin pharmacokinetics in South African pulmonary TB infected adults
Thursday 16 October, 2025
Introduction: The treatment of TB requires the use of multiple drug containing regimens. As rifampicin (RMP) has the ability to…
Read morePopulation Pharmacokinetics of Vancomycin in Iranian Paediatric Patients
Thursday 16 October, 2025
Objectives: The pharmacokinetic profile of vancomycin (VCM) differs between paediatrics and adult patients, therefore understanding VCM pharmacokinetics in paediatric patients…
Read morePopulation pharmacokinetics of antimalarial drugs in the treatment of pregnant women with uncomplicated malaria
Thursday 16 October, 2025
Objectives: Pregnancy has considerable effects on the pharmacokinetic properties of many of the drugs used to treat uncomplicated falciparum malaria….
Read morePopulation pharmacokinetics of lumefantrine in pregnant women treated with co-artemether for uncomplicated falciparum malaria
Thursday 16 October, 2025
Objectives: The fixed combination of artemether and lumefantrine (co-artemether) is today the most widely used co-formulated artemisinin-based antimalarial combination therapy…
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