Objectives: The Neumann’s model of viral dynamics is the standard explanation for the biphasic decline of Hepatitis C virus (HCV)…
Read morePoster: Applications- Anti-infectives
Population Pharmacokinetics Of Vancomycin In Tunisian Patients
Objectives: Vancomycin (VCM) is a glycopeptide antibiotic generally used for the treatment of gram-positive infections. For individualized optimal VCM dosage…
Read morePopulation pharmacokinetic analysis of ciprofloxacin in intensive care unit adult patients
Objectives: To propose optimal dosage regimens for Intensive Care Unit (ICU) patients in order to achieve relevant PK/PD targets. It…
Read morePopulation Pharmacokinetics of Amikacin in Korean Clinical Population
Objectives: This study aimed to develop a pharmacokinetic model of amikacin and to assess the influence of demographic and clinical…
Read moreEffect of Various Meals on the Population Pharmacokinetics of Rifapentine
Objectives: Rifapentine and its primary metabolite, 25-desacetyl rifapentine, are active against mycobacterium tuberculosis. The objectives of this study were to…
Read moreOptimal Dosing of Miltefosine in Children and Adults with Leishmaniasis
Introduction & Objectives: Pharmacokinetics and –dynamics (PK/PD) of miltefosine in children suffering from visceral leishmaniasis (VL), a fatal neglected parasitic…
Read moreApplications of Discrete-Event Dynamic Simulation in HCV Treatment Dynamics
Backgrounds: The treatment objective in patients chronically infected with Hepatitis C Virus (HCV) is viral eradication, which allows patients to…
Read morePopulation pharmacokinetic modeling and optimal sampling strategy for Bayesian estimation of amikacin in critically ill septic patients
Objectives: In severe sepsis and septic shock, appropriate antibiotic therapy plays a key role in the patient management. Since the…
Read moreApplication of systems pharmacology modeling approach to optimize Interferon therapy of hepatitis C
Motivation: The interferon-based therapy is a common method of hepatitis C treatment. However, interferon-based therapy is lengthy (48 weeks), expensive…
Read moreApplication of pharmacokinetic-pharmacodynamic model to optimize dosing regime of antimicrobial drug Grammidin containing gramicidin S
Objectives: To predict the dependence of antimicrobial effect of the gramicidin S applied as oral melting tablets on dosage, time…
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