Abstracts - PAGE Meeting (Population Approach Group Europe)

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Abstracts (24)

I-100Jamilah Alnahdi

Model-Informed Drug Development at Sِaudi FDA: Approaches, Applications, and Regulatory Impact

Wed, Jun 3, 2026 10:00AM–12:00AM

I-101Stephanie Kollmann

monolixSuiteTFL: AN R PACKAGE FOR AUTOMATED TABLES, FIGURES AND LISTINGS FROM MONOLIXSUITE PROJECTS

Wed, Jun 3, 2026 10:30AM–12:00PM

I-102Victor Sokolov

SimuRg: an R wrapper package for an AI-based pharmacometrics ecosystem

Wed, Jun 3, 2026 10:30AM–12:00PM

I-103Carla Troisi

STREAMLINED OPEN-SOURCE PBPK DDI ASSESSMENTS USING THE OSP SUITE WITH R-BASED esqlabsR/ESQapp WORKFLOWS

Wed, Jun 3, 2026 10:30AM–12:00PM

I-104Lisa Wellin

POPULATION PHARMACOKINETIC MODELLING TO SUPPORT BIOEQUIVALENCE ASSESSMENT OF GENERIC DRUGS: AN ILLUSTRATIVE SIMULATION STUDY USING AMODIAQUINE.

Wed, Jun 3, 2026 10:30AM–12:00PM

I-105Han Zheng

COMPARISON OF MASPECTRA AND NONMEM FOR POPULATION PHARMACOKINETIC MODELING: AN ABSK-011 (IRPAGRATINIB) CASE STUDY

Wed, Jun 3, 2026 10:00AM–12:00AM

II-100Muriel Boulton

Choosing the Right Exposure Metric: Power and Confounding in Exposure-Response (E-R) Models

Wed, Jun 3, 2026 3:20PM–4:50PM

II-101Ari Brekkan

Use the AUC and discard Cmax in exposure-response analysis

Wed, Jun 3, 2026 3:20PM–4:50PM

II-102Meemansa Sood

Enhancing Data Sharing and Anonymization to Enable Model-Based Approaches and Virtual Patient Cohorts in the INVENTS Project

Wed, Jun 3, 2026 3:20PM–4:50PM

II-103Elodie Valade

Impact of Below Limit of Quantification (BLQ) Concentrations handling strategies on Concentration-QTc analysis

Wed, Jun 3, 2026 3:20PM–4:50PM

II-104Kohei Yamaguchi

METHODS FOR SUBGROUP SIMILARITY ASSESSMENT IN DOSE-RESPONSE META-ANALYSIS USING A BOOTSTRAP APPROACH

Wed, Jun 3, 2026 3:20PM–4:50PM

II-105Manuela Zimmermann

A POTENTIAL COST OF BLOCK-DIAGONAL Ω:
BIASED DOSE-RESPONSE ESTIMATES IN THE PRESENCE OF EXPOSURE-RESPONSE CONFOUNDING

Wed, Jun 3, 2026 3:20PM–4:50PM

III-100Happy Djokoto

QUANTIFYING THE IMPACT OF LLOQ AND ULOQ CENSORING ON M3 ESTIMATION PERFORMANCE IN NONMEM

Thu, Jun 4, 2026 9:50AM–11:20AM

III-101Anna Mikhailova

R-based Bayesian workflow for ODE pharmacometrics modeling: generalized dapagliflozin PK model as a case study

Thu, Jun 4, 2026 9:50AM–11:20AM

III-102Arno Strouwen

InVitroInVivoCorrelation.jl: A MODULAR JULIA PACKAGE FOR LEVEL A IVIVC

Thu, Jun 4, 2026 9:50AM–11:20AM

III-103Igor Vasyutin

The Decision-Equivalence Metric (DEM) Method Based Evaluation of Biomarker Surrogacy in MASH

Thu, Jun 4, 2026 9:50AM–11:20AM

III-104Koichiro Yoneyama

COUNTING THE BIOCHEMICAL REACTION OCCURRENCES: A STATISTICAL IMPLICATION OF THE FIRST-ORDER RATE CONSTANTS IN KINETIC MODELS

Thu, Jun 4, 2026 9:50AM–11:20AM

IV-099Isabelle ALAKIKI

CROSS-PLATFORM REPRODUCIBILITY OF POPULATION PHARMACOKINETIC MODELING: TRANSLATION FROM NONMEM TO PUMAS