GastroPlusTM is an advanced technology computer program that simulates gastrointestinal absorption and pharmacokinetics, and optionally, pharmacodynamic effects, for drugs dosed…
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Hands-On Demonstrations of the Physiology-Based Pharmacokinetic Software, PK-Sim®
PK-Sim(R) is a software tool for physiology-based pharmacokinetic whole-body modelling in laboratory animals (mouse, rat, dog) and humans. It is designed…
Read moreTransforming a set of office computers to a computing cluster.
Objectives: Population PK/PD model building and evaluation potentially involves methods that use a large number of independent executions of regression…
Read moreA4S: a user-friendly PKPD simulation software for non experts
Objectives: Effective communication of PKPD principles and results in a biomedical research environment remains a significant challenge [1], which can…
Read morePulmoSim: A Physiologically-Based Mathematical Model Software Package to Predict Lung Retention and Inhaled Pharmacokinetics of Therapeutic Candidates
Objectives: Retention within the lung tissue is widely believed to enhance the duration of action of inhaled therapeutics. However, the…
Read moreMetworx: high-performance cloud computing made simple
METWORX is high-performance cloud computing made simple. On-demand and with just a few clicks, METWORX will build and configure your…
Read moreDevelopment and Evaluation of a New Efficiency Tool (SADAPT-TRAN) for Model Creation, Debugging, Evaluation, and Automated Plotting using Parallelized S-ADAPT, Perl and R
Objectives: 1) To develop an efficiency tool (SADAPT-TRAN) as an add-on for S-ADAPT that greatly facilitates nonlinear mixed-effects modelling and…
Read moreiClinical: NONMEM Workbench
NONMEM is a widely used application for population-based PK/PD analyses. The application offers limited output capabilities and subsequent data reduction…
Read moreSoftware using Physiologically Based Finite Time Pharmacokinetic (PBFTPK) Models
Introduction: The collapse of the physicomathematical fallacy of infinite time of oral drug absorption (1-4), was followed by the development…
Read moreMango Solutions
Mango Solutions provide software services to PK/PD groups working in the pharmaceutics industry. This includes training and direct consulting in…
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