Objectives: Calibrating Quantitative Systems Pharmacology (QSP) models requires reliable comparisons between simulations and in vivo baseline data, such as cytokine…
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LikelihoodProfiler.jl: A Unified Package for Practical Identifiability Analysis and Confidence Intervals Estimation
Introduction. Practical identifiability addresses the crucial question of how well a model (particularly Systems Biology/Quantitative Systems Pharmacology (SB/QSP) model) is…
Read moreOpen source software from the Uppsala University Pharmacometrics group
The Uppsala University pharmacometrics group develops and maintains several different open-source software packages. ncappc – Performs traditional non-compartmental analysis and…
Read moreThe optiDoseR package – facilitating application of OptiDose in R, NONMEM and Monolix
Objectives The optimal drug dosing algorithm OptiDose, recently implemented in NONMEM [1,2], allows users to solve their own optimal dosing…
Read moreTitle: turbocharging computation efficiency: a tutorial on hierarchical parallel computing in r
Background: In modern computational tasks across various fields, such as pharmacometrics, statistical modeling, and data analysis, handling large datasets and…
Read moreAPIS : A software for clinical and experimental pharmacokinetics
APIS is a software package based on mathematical modelling which provides a reliable approach in optimising drug therapy. It was…
Read moreMicroPharm Population (MP2) – An interactive and user-friendly interfaced program for population pharmacokinetics.
This project is developed for population pharmacokinetic modeling of experimental data. The program is written in Pascal language based on…
Read moreNPEM2: A Nonparametric Program Useful For Clinical Uses : Both Population Pharmacokinetic Modeling, Leading To “Multiple Model” (MM) Adaptive Control
Schumitzky has recently developed a nonparametric expected EM algorithm that represents another approach to the method of Mallet, who introduced…
Read moreP-PHARM: A Population Pharmacokinetic-Pharmacodynamic Data Modeling Software
P-Pharm is a computer program designed for fitting a general nonlinear regression model to data. The data analyzed is typically…
Read morePOPKAN – Population Pharmacokinetic Analysis using Bayesian Inference
POPKAN is a computer program that carries out the Bayesian analysis of population pharmacokinetic data. The program is menu-driven, is…
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