Objectives: The burden of childhood diarrhea and malnutrition remains high in South Asia due to inadequate household sanitation, lack of access…
Read morePoster: Methodology - New Modelling Approaches
Identification of foods with optimal nutritional value through data mining.
*Contact :- Jens Nielsen, email:- nielsenj@chalmers.se Background: Exclusive breastfeeding for 6 months has been shown to be the optimal way…
Read moreA mechanistic maternal-fetal growth energy budget model
Background: Metabolic cost and metabolic consequences due to metabolic adjustments occurring during pregnancy and lactation to support fetal growth and…
Read moreCompetitive brain and body growth model
Objectives: Malnutrition has a considerable effect on the body development during childhood and, in particular, it affects brain development and cognitive…
Read moreThe drug titration paradox in the presence of intra-individual variation: can we estimate the true concentration-effect relationship?
Objectives: The drug titration paradox arises when higher drug concentrations are paradoxically associated with poorer efficacy outcomes, due to the titration…
Read moreBayesian hierarchical model of glucose-insulin regulation over 12-week home use of closed-loop insulin delivery
Objectives: Parameters of physiological models of glucose-insulin regulation in type 1 diabetes have been estimated using data collected over a relatively…
Read moreA model-based approach for joint analysis of pain intensity and opioid consumption in postoperative pain
Objectives: Joint analysis of pain intensity and opioid consumption is encouraged in trials of postoperative pain [1]. However, previous approaches have…
Read moreLongitudinal Model-Based Meta-Analysis (MBMA) for rheumatoid arthritis with Monolix
Objectives: Model-based meta-analysis (MBMA) uses published aggregate data from many studies to develop a study-level model and support the decision process. Because in an…
Read moreA comparison between nonlinear mixed effects and naïve pooled data methods in population PK model selection
Objectives: It is recognized that nonlinear mixed effect (NLME) models are a more appropriate representation of data from multiple subjects than…
Read moreHigh-Resolution Image-based Computational Modeling of Breast Tumor Microvasculature
Objectives: The goal of the project is to develop a computationally intensive model to characterize a whole human tumor xenograft comprised…
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