Thursday 16 October, 2025
Objectives: Spinal anesthesia with levobupivacaine and ropivacaine is widely used due to its favorable safety and efficacy profiles. Although previous…
Read morePoster: Clinical Applications
Optimizing vancomycin dosing in older patients: predictive performance of pharmacometrics models
Thursday 16 October, 2025
Introduction: Intravenous vancomycin is commonly used to treat severe gram-positive infections in older adults (=75 years). Yet, its narrow therapeutic…
Read moreUnraveling the PK of target site cefuroxime exposure in prosthetic joint infection patients: a population PK analysis
Thursday 16 October, 2025
Objectives: Prosthetic joint infection (PJI) is a common and growing reason for prosthetic joint replacement in patients that underwent total…
Read moreA joint pharmacometric model of iohexol and creatinine administered through a meat meal to assess GFR and renal OCT2/MATE activity
Thursday 16 October, 2025
Introduction: Accurately assessing glomerular filtration rate (GFR) based on plasma creatinine concentrations is challenging in patients with unstable renal function….
Read morePopulation pharmacokinetics of cenobamate and dose rationale for its use in paediatric patients affected by focal onset and primary generalized tonic-clonic seizures.
Thursday 16 October, 2025
Objectives: Epilepsy is a chronic disorder affecting 50 million people worldwide, including 450,000 children(1-5). Cenobamate (CNB) has been approved for…
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