Thursday 16 October, 2025
Objectives: The aim of the study was to investigate the influence of valproic acid (VPA) daily dose on its oral…
Read morePoster: Applications- CNS
Population Pharmacokinetic Modelling of Amitriptyline in Depression Patients
Thursday 16 October, 2025
Objectives: This study aimed to characterize population pharmacokinetics of amitriptyline (AMT), in order to identify possible influential covariates and to…
Read morePooled PK analysis of a new CNS drug, in healthy subjects.
Thursday 16 October, 2025
Objectives: The objectives of the pooled data analysis were to describe the PK of a new drug developed in the…
Read morePopulation pharmacokinetic analysis in children, adolescents and adults with schizophrenia or bipolar disorder
Thursday 16 October, 2025
Introduction: Risperidone is an effective and well-tolerated atypical antipsychotic. Oral risperidone is licensed for the treatment of schizophrenia and acute…
Read moreRetrospective population pharmacokinetic analysis of seletracetam in epileptic and healthy adults
Thursday 16 October, 2025
Objectives: Characterization of population pharmacokinetics of the novel SV2A ligand seletracetam (ucb 44212) in healthy and epileptic adult populations to…
Read moreEstimation of Relative Bioavailability of Controlled-Release Carbamazepine Tablets Based on Routine TDM Data
Thursday 16 October, 2025
Objectives: Controlled-release (CR) formulation of carbamazepine (CBZ) tablets, in contrast to immediate-release (IR) form, show lower peak-trough fluctuation of CBZ…
Read moreUse of Routine Data for Determination of the Population Pharmacokinetics and Enteral Bioavailability of Phenytoin in Neonates and Infants with Seizures
Thursday 16 October, 2025
Objective: To investigate the population pharmacokinetics and the enteral bioavailability of phenytoin in neonates and infants with seizures. Methods: Data…
Read morePopulation Pharmacokinetics of Brivaracetam in Patients with Partial Epilepsy
Thursday 16 October, 2025
Objectives: To model the population pharmacokinetics of brivaracetam (BRV), a novel antiepileptic drug (AED) in development, in refractory patients with…
Read moreSwitching to Paliperidone Palmitate[1,2] from Other Depot Antipsychotics: Guidance Based on Pharmacokinetic Simulations
Thursday 16 October, 2025
Objective: Population PK models have been developed for paliperidone palmitate (PP) and risperidone long-acting injection (RLAI) based on data from…
Read moreConcentration-response analysis of antipsychotic drug effects using an indirect response model
Thursday 16 October, 2025
PDF of poster Objectives: The effect of antipsychotics is typically assessed using various scales reflecting the clinical status of patients….
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