Thursday 16 October, 2025
PDF of posterObjectives: To explore the PK-PD relationship of meropenem in febrile neutropenic patients in Korea. Methods: Fifty seven febrile…
Read morePoster: Applications- Anti-infectives
A Population Pharmacokinetic Model for the Simultaneous Description of Linezolid Tissue and Plasma Disposition in Healthy Volunteers and Septic Patients
Thursday 16 October, 2025
PDF of posterObjectives: Linezolid, the first member of the oxazolidinones, has been approved for the treatment of severe gram-positive infections….
Read morePK-PD modelling to support go/no go decisions for a novel gp120 inhibitor
Thursday 16 October, 2025
Objectives: PF-00821385 is a specific inhibitor of HIV-1 gp120 mediated cell-cell fusion. Inhibitors of HIV-1 gp120 represent a novel mechanistic…
Read moreCiprofloxacin Integrated Plasma, Saliva and Sweat Population Pharmacokinetics and Emergence of Resistance in Human Commensal Bacteria
Thursday 16 October, 2025
Objectives: Emergence of resistance to fluoroquinolones is an increasing therapeutic problem (1). One of the routes for resistance development is…
Read morePharmacokinetic-Pharmacodynamic Modelling for Antibiotics: Static and Dynamic In Vitro Time-Kill Curve Experiments
Thursday 16 October, 2025
Objectives: In vitro time-kill studies are commonly conducted with the aim to assess efficacy of antimicrobial agents. Previously a general…
Read moreDevelopmental Pharmacokinetics of Gentamicin in Preterm and Term Neonates: Modelling and Simulation Based on Data from a Prospective Study
Thursday 16 October, 2025
Objectives: Knowledge and use of predictive covariates could lead to faster attainment of therapeutic gentamicin levels and reduce the need…
Read morePopulation Pharmacokinetics of Gentamicin in Preterm and Term Newborn Infants
Thursday 16 October, 2025
PDF of poster Objectives: Gentamicin is an aminoglycoside antibiotic commonly used in the prophylaxis and treatment of gram negative infections…
Read moreEffect of CYP2C19 polymorphism on nelfinavir to M8 biotransformation in HIV patients.
Thursday 16 October, 2025
Objectives: To evaluate the effect of CYP2C19 polymorphism on nelfinavir and M8 pharmacokinetic variability in HIV infected patients and to…
Read moreUse of Eltrombopag Exposure-Platelet Response Relationship for Dose Optimization in Patients with Chronic HCV-Infection with and without Interferon
Thursday 16 October, 2025
Objectives: Eltrombopag is the first oral small-molecule, non-peptide thrombopoietin receptor agonist. It is under development for the treatment of thrombocytopenia…
Read morePenetration of Isoniazid, Rifampicin, Pyrazinamide and Moxifloxacin into Pulmonary TB Lesions in Rabbits
Thursday 16 October, 2025
Background: About one third of the world's population has latent tuberculosis (TB), whereof about nine million cases of active tuberculosis…
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