Oral Presentation: Applications

How Disease Models can reduce late phase attrition rate to half by 2015

Thursday 16 October, 2025

Only 5% of new molecules make it to the market in oncology, lowest compared to other therapeutic areas. Yet, cancer…

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Effect of Cranberry Juice on Population Pharmacokinetics of Amoxicillin and Cefaclor

Thursday 16 October, 2025

Objectives: Consumption of cranberry juice with low-dose oral antibiotics is often prescribed as long-term therapy/prophylaxis for recurrent urinary tract infection….

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Individualized compared with conventional dosing of enoxaparin.

Thursday 16 October, 2025

Introduction: There is widespread belief that individualizing dosing regimens of drugs will further optimize outcomes for each patient. However there…

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Models of Glucose Metabolism and Control in Diabetes

Thursday 16 October, 2025

Diabetes is one of the major chronic diseases, i.e. together with its complications it accounts for more than 10% of…

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Kinetic models of PSA decrease after surgery in prostate tumor diseases as a help for clinician interpretation

Thursday 16 October, 2025

Objectives: In order to characterize Prostate Specific Antigen (PSA) compartments releases (anatomy transitional and peripheral zones) and prognostic value of…

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Model-based dose adaptation of capecitabine for prevention of severe hand-and-foot syndrome: in silico comparison with the standard method

Thursday 16 October, 2025

Introduction: Management of anticancer therapies is complex due to their narrow therapeutic indices (interval between minimum effective and toxic doses) and…

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Deconvolution of Insulin Secretion Rates

Thursday 16 October, 2025

Abstract is based on Master Project [4] and article [3] by Soren Klim and Stig Mortensen Objectives: Insulin and C-peptide…

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Planning To Communicate

Thursday 16 October, 2025

Objectives: As a discipline, Pharmacometics has matured to the point where no educated observer doubts that a skilled pharmacometrician can…

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Simulation of the Nonlinear PK of Gabapentin and Midazolam in Adult and Pediatric Populations

Thursday 16 October, 2025

PDF of presentationObjective: Demonstrate building GastroPlus(tm) models for the nonlinear dose dependencies for gut transporter and gut enzyme substrates in…

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Cystatin C as a new covariate to predict the renal elimination of drugs

Thursday 16 October, 2025

Objectives. Individual dosing of drugs mainly eliminated by renal excretion is possible by estimation of the renal function. Most of…

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