28th PAGE Meeting

Stockholm - Sweden
11-14 June, 2019

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Abstracts (18)

I-14Hesham Al-Sallami

The use of a Bayesian dosing tool to optimise enoxaparin treatment: a pilot clinical study

Wednesday 09:50-11:15

I-24Geraldine Celliere

Straightforward dose adaptation simulations with Simulx, the simulator of the MonolixSuite

Wednesday 09:50-11:15

I-34Carla Bastida Fernández

Assessment of tapering strategies for intravenous tocilizumab in rheumatoid arthritis patients

Wednesday 09:50-11:15

I-49Thomas Bouillon

Model predictive control with Bayesian updates (MPC) is more robust to model misspecification, compared to standard Bayesian control (sEBE) for Therapeutic Drug Management (TDM). Investigation in a cohort of 315 patients receiving tacrolimus during the first 14d after renal transplantation.

Wednesday 09:50-11:15

I-62Jantine Brussee

Model-based dose optimization of ivermectin to achieve equivalent exposure coverage in children and adults

Wednesday 09:50-11:15

I-64Dong Woo Chae

Predictive model of postoperative nausea and vomiting in patients treated with Fentanyl-based intravenous patient controlled analgesia

Wednesday 09:50-11:15

I-67Christophe Chassagnole

A precision dosing application for docetaxel in metastatic prostate cancer

Wednesday 09:50-11:15

I-69Jonathan Chauvin

Novel user-friendly applications for dose individualization of sunitinib and imatinib

Wednesday 09:50-11:15

I-85Laurence Del Frari

Population modelling and simulations of binimetinib pharmacokinetics in subjects with hepatic impairment to explore optimal dosing regimen using total and unbound binimetinib exposures

Wednesday 09:50-11:15

II-16Rory Leisegang

Establishing evidence for improved outcomes for HIV+ patients receiving antiretroviral drugs through home delivery

Wednesday 15:10-16:40

II-32Guangda Ma

Evaluating the influence of genotype on warfarin dose predictions made using a theory-based PKPD model.

Wednesday 15:10-16:40

III-18Christian Siebel

Development of an adaptive dosing approach for doxorubicin in paediatric cancer patients

Thursday 09:55-11:20

III-21Noppaket Singkham

Pharmacogenetics-Based Population Pharmacokinetic Analysis for Dosing Optimization of Ritonavir-Boosted Atazanavir in Thai adult HIV-Infected Patients

Thursday 09:55-11:20

IV-03Erwin Dreesen

A population pharmacokinetic and exposure-response model to support therapeutic drug monitoring during vedolizumab induction therapy

Thursday 15:25-16:50

IV-39Tingjie Guo

Exploring practical limitations of model-based Bayesian dose optimization in intensive care patients

Thursday 15:25-16:50

IV-46Emilie Hénin

Therapeutic drug monitoring strategies for Envarsus in de novo renal transplant patients using population modelling and simulations

Thursday 15:25-16:50

IV-52Nick Holford

Rational dosing of caffeine using target concentration intervention to improve treatment of apnea of prematurity

Thursday 15:25-16:50

IV-79Ron Keizer

Continuous learning in model-informed precision dosing: a case study

Thursday 15:25-16:50