| Thursday June 15 |
| 08:00-08:40 |
Registration and coffee |
| 08:40-09:00 |
Welcome and Introduction |
|
Oral session I |
COSTB15 session (1) |
chair: Leon Aarons |
| 09:00-09:05 |
Leon Aarons |
Introduction: COSTB15 |
| 09:05-09:25 |
Mats Karlsson |
A report on an expert meeting to discuss the role of modelling in Phase I clinical drug development |
| 09:25-10:00 |
David Giltinan |
Population PK/PD Modeling in Drug Development: A Case Study |
| 10:00-11:30 |
Poster and software session I |
|
Oral session II |
COSTB15 session (2) |
chair: Rene Bruno |
| 11:30-12:05 |
Lewis Sheiner |
Model Evaluation: Some Preliminary Experience with the Posterior Predictive Check |
| 12:05-12:30 |
France Mentre |
Validation methods in population pharmacokinetics: a new approach based on predictive distributions with an evaluation by simulation |
| 12:30-14:00 |
Lunch |
|
Oral session III |
Paediatrics/Clinical applications |
chair: Tom Ludden |
| 14:00-14:35 |
Alison Thomson |
Population pharmacokinetics in paediatric patients -- the good, the bad and the ugly |
| 14:35-15:00 |
Rik Schoemaker |
In search of an optimal furosemide infusion strategy in children after cardiac surgery using modelling and simulation |
| 15:00-15:20 |
Iñaki f. Trocóniz |
Pharmacokinetic/pharmacodynamic modeling of the antipyretic effect of two oral formulations of ibuprofen: suspension and effervescent granules |
| 15:20-15:40 |
Emmanuelle Comets |
Evaluation of tests based on individual versus population modelling to compare dissolution curves |
| 15:40-16:00 |
Roberto Gomeni |
Population pk/pd of craving symptoms in an enforced smoking cessation population: probabilistic and indirect modelling approach |
| 16:00-17:00 |
Poster and software session II |
| 17:00-17:30 |
Session honoring Alison Boeckmann |
|
Stuart Beal, Tom Ludden, Pascal Girard, Brigitte Tranchand |
|
| 20:30- open |
Social event |
|
|
| Friday June 16 |
|
Tutorial |
|
chair: France Mentré |
| 08:45-09:30 |
Stuart Beal |
Things you may have wanted to ask about the $ESTIMATION record but have been hesitant to ask |
|
Oral session IV |
|
chair: France Mentré |
| 09:30-09:50 |
Eugène Cox |
Population pharmacodynamic model for count data: application to clinical trial simulations for compound PH2000 for the improvement of the number of satisfying events |
| 09:50-10:10 |
B. Vrijens |
The impact of patient compliance in pharmacokinetic/pharmacodynamic studies |
| 10:10-11:45 |
Poster and software session III |
|
PAGE session |
|
chair: David Tudor |
| 11:45-11:55 |
David Tudor |
Presentation of next year's PAGE meeting, miscellaneous information and call for new OC members |
|
Oral session V |
Advances in population analysis |
chair: David Tudor |
| 11:55-12:25 |
Paul Williams |
The Application of Resampling Methods to Population Pharmacokinetics |
| 12:25-12:55 |
Didier Concordet |
Checking departure from normality of the random effects |
| 12:55-13:25 |
Stephen Duffull |
Optimal design of population pharmacodynamic experiments |
| 13:25-13:45 |
Sylvie Retout |
Optimal population designs for enoxaparin pharmacokinetics: evaluation by simulation |
| 13:45-14:00 |
Closure followed by light lunch |
