| Friday June 25 | |||
| 09:00-09:45 | Registration | ||
| 09:45-10:00 | Welcome | ||
| Oral session I | Software | chair: A. Thomson | |
| 10:00-10:15 | C. Pobel | NONMEM running on a PC workstation: installation and use in a Clinical Pharmacy Department | |
| 10:15-10:30 | P. Girard, A. Laffont, J.P. Boissel | Interface between NONMEM output and an Exploratory Data Analysis Tool | |
| 10:30-10:45 | D. Stephens | The POPKAN Software | |
| 10:45-11:00 | R. Gomeni | P-Pharm : A Population Pharmacokinetic-Pharmacodynamic Data Modeling Program | |
| 11:00-11:30 | Coffee break | ||
| Oral session II | Comparison of methodologies | chair: W. Weber | |
| 11:30-12:00 | J. Wakefield | Comparison of approaches - Population Pharmacokinetics of Quinidine | |
| 12:00-12:15 | N. Best, W. Gilks, K. Tan | Population Pharmacokinetic Modelling using the GIBBS Sampler | |
| 12:15-12:30 | M.C. Iliadis, R. Bruno, V. Cosson, J.C. Vergniol, A. Mallet, G. Montay, D. Oulid-Aissa, M. Marty, M. Clavel, M. Aapro, A. Frydman, M. Bayssas, A. Iliadis | Taxotere Population Pharmacokinetics during Phase I Studies : Comparison of NONMEM and NPML | |
| 12:30-12:45 | E. Fuseau, S. Lettis, L. Lacey | Simulated Population Pharmacokinetic Data for Use in Assessing the Robustness of Current Population Methods | |
| 12:45-14:00 | Lunch | ||
| Oral session III | chair: J. Van Bree | ||
| 14:00-14:15 | L. Aarons | The use of an EM algorithm for parameter estimation from spare data | |
| 14:15-14:30 | F.Y. Bois, D. Maszle, A. Gelman | A Toxicokinetic Analysis of Tetra Chloroethylene Methabolism in Humans | |
| 14:30-14:45 | L.S. Murray, S. Senan, J. Cassidy, P. Workman, S.B. Kaye, M.A. Graham | A Preliminary report on the Pharmacokinetics of Tirapazamine | |
| 14:45-15:00 | C. Laveille, M. Chic, F. Dubois, R. Jochemsen | Indapamide population pharmacokinetics via mixed effects modeling: models building and bayesian estimation of pharmacokinetics parameters | |
| 15:00-15:15 | W. Weber, L. Harnisch | Population pharmacokinetics in paediatric patients : comparison of empirical renal clearance models | |
| 15:15-15:30 | A. Laffont, P. Girard, P. Maire, X. Barbaut, G. Chapelle, C. Pobel, T. Berod, C. Pivot, B. Lacarelle, J. Debord, R.W. Jelliffe, J.P. Boissel | Multicenter study of Amikacyn Pharmacokinetics from patients under TDM | |
| 15:30-15:45 | N. Taright, F. Mentré, R. Jouvent, S. Ammar, A Mallet | Population analysis of the kinetics of litium using NPML and evaluation of the estimated characteristics on a group of patients regimen | |
| 15:45-16:30 | Tea break | ||
| Tutorial | chair: S. Vozeh | ||
| 16:30-17:30 | F. Mentré | Optimal Design in Population Analysis Including Bayesian Aspects | |
| Oral session IV | Population approach in Drug Development | chair: S. Vozeh | |
| 17:30-17:45 | J.L. Steimer | Points to consider when presenting population analysis to regulatory autorities | |
| 17:45-18:00 | A. Van Peer | International Harmonisation of Guidelines on Studies in Special Patient Populations | |
| 18:80-18:15 | R. Bruno, T. Joumard, N. Vivier, J.C. Vergniol, V. Cosson, G. Montay, F. This, M. Bayssas, A. Frydman | Implementation of Population Pharmacokinetic Studies during Drug Development : Success Factors | |
| 18:15-18:30 | PAGE prospects : general discussion (R. Bruno, P. Girard, J.L. Steimer, B. Tranchand) COST B1 - Next meeting(s) ? - Organizing Committee | ||
| 18:30 | End of the meeting | ||
2th PAGE Meeting
- Paris - France
- 25 June, 1993
