Frederic Y. Bois, Don Maszle, Andrew Gelman
Faculté des Sciences Pharmaceutiques, Nancy, Bioengeneering Program, UC Berkeley, Statistics Department, UC Berkeley.
A physiological toxicokinetic model was used to describe the distribution and metabolism of tetrachloroethylene (TCE) in a human population. Data on TCE exposures were provided for each individual and included specific covariates. A random effect model was developed to describe population variability. The model was parametrized using Gibbs sampling, in a Bayesian context. We discuss the advantages and drawbacks of the method, as we experienced them.
Reference: PAGE 2 () Abstr 907 [www.page-meeting.org/?abstract=907]
Poster: oral presentation