Objectives: Imipenem is often used for empirical treatment of ventilated-associated pneumonia (VAP). Large interindividual variations in the pharmacokinetic parameters (PK)…
Read morePoster: Infection
Pharmacokinetic/Pharmacodynamic modeling of time-kill curves for echinocandins against Candida.
Objectives: In vitro time-kill studies are commonly used in the assessment of efficacy of antimicrobial agents. The aim of the…
Read moreSimulations to investigate new Intermittent Preventive Therapy Dosing Regimens for Dihydroartemisinin-Piperaquine
Objectives: A fix combination of dihydroartemisinin (DHA)-piperaquine (PQ) has been suggested as a new alternative for Intermittent Preventive Therapy (IPT)…
Read moreA dynamically integrative PKPD model to predict the efficacy of marbofloxacin treatment regimens for bovine Mannheimia hemolytica infection
Objectives: To develop a PKPD model that dynamically integrates in vitro and in vivo data, specifically the pharmacokinetics of marbofloxacin…
Read morePopulation Pharmacokinetics of Piperacillin in Burn Patients
Objectives: Piperacillin-tazobactam is a parenterally administered combination of β-lactam antibiotic/β-lactamase inhibitor. It shows broad antibacterial activity against Pseudomonas aeruginosa and…
Read morePopulation Pharmacokinetics of Emtricitabine in HIV-1-infected Patients
Objectives: The aim of this study was to describe the pharmacokinetics of emtricitabine (FTC) in a large population of HIV-1-infected…
Read morePopulation pharmacokinetic analysis of colistin after administration of inhaled colistin methanesulfonate.
Objectives: Colistin is an antimicrobial agent administered to treat multidrug-resistant gram-negative bacterial infections [1]. The aim of the present study…
Read moreA Microdialysate-based Integrated Model with Nonlinear Elimination for Determining Plasma and Tissue Pharmacokinetics of Linezolid in Four Distinct Populations
Objectives: Linezolid (LZD) provides a valuable treatment option in a wide range of infections across variant patient groups. Sufficient drug…
Read moreA Proposed Adaptive Feedback Control (AFC) Algorithm for Linezolid (L) based on Population Pharmacokinetics (PK)/Pharmacodynamics (PD)/Toxicodynamics(TD)
Objectives:L has a complicated &variable population PK model with parallel saturable (non-renal) & first order (renal) pathways of elimination. The…
Read morePopulation Pharmacokinetics of Cefuroxime in patients Undergoing Colorectal Surgery
Objectives: The aim of this study is to develop a population pharmacokinetic model for cefuroxime used as prophylaxis in patients…
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