Poster: Drug/Disease Modelling - Endocrine

Quantification of tetracosactide (synthetic ACTH) pharmacokinetics and its effects on cortisol production in healthy adults and children

Thursday 16 October, 2025

Introduction and Objectives Congenital adrenal hyperplasia patients exhibit cortisol deficiency and often require lifelong cortisol replacement therapy. To optimise this…

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Pharmacokinetic Modeling of Enavogliflozin, a Sodium Glucose Co-transporter 2 Inhibitor, in Korean Healthy Volunteers and Patients with Type 2 Diabetes Mellitus

Thursday 16 October, 2025

Objectives: Enavogliflozin is a novel sodium-glucose cotransporter 2 inhibitor developed for the treatment of type 2 diabetes mellitus (T2DM). This…

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Longitudinal Biomarker Modeling of T2D-Patients Treated With Semaglutide

Thursday 16 October, 2025

Introduction: Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has emerged as a significant advancement in the treatment of type 2…

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Comparison of immediate- and modified-release hydrocortisone to achieve therapeutic goals in congenital adrenal hyperplasia

Thursday 16 October, 2025

Introduction and objectives: Congenital adrenal hyperplasia (CAH) is a rare genetic disease characterised by reduced cortisol production. Cortisol production is…

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A Population-based Time-to-Event Model for Pregnancy Loss Risk Prediction in frozen-thawed embryo transfer (FET)

Thursday 16 October, 2025

BACKGROUND: Pregnancy loss (PL) after FET imposes significant physiological and mental burden on the patients, and reduced success rates of…

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