Thursday 7 May, 2026
Objectives Tacrolimus is the cornerstone immunosuppressant after intestinal transplantation, a rare but life saving option for irreversible complicated intestinal failure….
Read morePoster: Clinical Applications
KPD-ML PREDICTION OF DOCETAXEL‑INDUCED NEUTROPENIA IN LARGE RWE DATASETS
Thursday 7 May, 2026
Introduction: Neutropenia remains a common and clinically important toxicity of cytotoxic chemotherapy, and early risk prediction is central to safer…
Read moreQUANTIFICATION OF INDIVIDUAL Î’-CELL FUNCTION AND INSULIN SENSITIVITY: TOWARDS PERSONALISED LIFESTYLE AND MEDICINE TREATMENT
Thursday 7 May, 2026
Objectives Type 2 diabetes mellitus (T2DM) is a major global health challenge, marked by insulin resistance and progressive dysfunction of…
Read morePOPULATION PHARMACOKINETIC-PHARMACODYNAMIC MODELLING OF FOLLICLE-STIMULATING HORMONE AND INHIBIN-B TO PREDICT OVARIAN RESPONSE TO FOLLITROPIN ALFA IN IN VITRO FERTILISATION PATIENTS
Thursday 7 May, 2026
Introduction/Objectives: Controlled ovarian hyperstimulation (COH) in women undergoing in vitro fertilisation (IVF) involves daily administration of recombinant follicle-stimulating hormone (FSH;…
Read moreDoes Nonlinear Absorption of Oral Misoprostol Challenge Guideline-Based Dosing in Late Pregnancy Cervical Ripening? A Population Pharmacokinetic Model to Resolve.
Thursday 7 May, 2026
Introduction: Misoprostol is the first-line agent for cervical ripening in late pregnancy, with oral administration increasingly superseding traditional vaginal routes…
Read moreProspective dose optimization for individual patients by successive application of empirical Bayesian estimation and OptiDose including uncertainty quantification: Application to pediatric Graves’ Disease
Thursday 7 May, 2026
Objectives In pediatric thyroid care, precise treatment is essential, as hormone imbalance can impair neurodevelopment, cognition, and growth. Despite guideline-based…
Read moreDolutegravir dose optimization based on population pharmacokinetics and pharmacogenetics in Thai people living with HIV
Thursday 7 May, 2026
Objectives: Dolutegravir (DTG), a second-generation integrase strand transfer inhibitor, is currently recommended as a first-line treatment for people living with…
Read moreTranslational PK/PD modelling of sofetabart mipitecan, an antibody-drug conjugate linked to exatecan via a novel cleavable polysarcosine linker
Thursday 7 May, 2026
Background Sofetabart mipitecan is a Fc-silent, FRα specific humanized IgG1 antibody-drug conjugate (ADC) linked to exatecan, a topo-I inhibitor, via…
Read moreProspective randomised controlled trial on model-informed precision dosing (MIPD) for ustekinumab and vedolizumab in inflammatory bowel diseases (MOVE-IT): A Bayesian framework incorporating parameter uncertainty
Thursday 7 May, 2026
Background Monoclonal antibodies (mAbs) such as infliximab, ustekinumab (UST), and vedolizumab (VDZ) represent effective treatment options for patients with inflammatory…
Read moreModeling of Vancomycin-Induced Changes in Serum Creatinine to Improve Prediction of Acute Kidney Injury
Thursday 7 May, 2026
Introduction: Vancomycin is an antibiotic commonly used in a hospital setting to treat Methicillin Resistant Staphylococcus Aureus (MRSA). The occurrence…
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