Thursday 16 October, 2025
Objectives: Nanobodies® are antibody-derived therapeutic proteins that contain the unique structural and functional properties of naturally-occurring heavy-chain antibodies. ALX-0081 is…
Read moreOral: Target mediated drug disposition
An integrated G-CSF-myelosuppression model characterizing the target mediated disposition of endogenous G-CSF in breast cancer patients following chemotherapy
Thursday 16 October, 2025
Objectives: Granulocyte colony stimulating factor (G-CSF) is the main regulating factor for neutrophils (ANC) and recombinant G-CSF is frequently used…
Read moreModeling of Drugs with Target-Mediated Disposition
Thursday 16 October, 2025
Objectives: To introduce Target-Mediated Drug Disposition (TMDD) model, discuss underlying assumptions and model properties, describe TMDD model approximations, discuss specific…
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