Oral: Real-world data (RWD) in pharmacometrics Archives - PAGE Meeting (Population Approach Group Europe)

A Novel Approach Using Pharmacometrics/Pharmacoeconomic (PMPE) Model for Cost-effectiveness Analysis of Tacrolimus-Diltiazem Combination in Liver Transplant Patients: Evidence from Real-world Clinical Data

Thursday 16 October, 2025

Introduction: Tacrolimus (TAC) is a typical immunosuppressant that is metabolized by the CYP3A4/CYP3A5 enzyme[1], commonly used in liver transplants to…

Overcoming the discrepancies between clinical trials and real-world data of small cell lung cancer chemotherapy. A data-driven approach to learn across real-world evidence studies

Thursday 16 October, 2025

Objectives: Since the 21st Century Cures Act in 2015, the potential for translating between real-world data (RWD) and clinical trials…

Virtual Patient Cohorts using Modeling and Simulation to support drug development in rare diseases

Thursday 16 October, 2025

Objectives: Rare diseases affect approximately 350 million people worldwide with only ~5% of diseases having approved treatments. Drug development in…

Streamlining Clinical Development of C.E.R.A. (Continuous Erythropoietin Receptor Activator) in Pediatric Chronic Kidney Disease Patients by Integration of Clinical Trial and Real-World Data

Thursday 16 October, 2025

Background: Methoxy polyethylene glycol‐epoetin beta or continuous erythropoietin receptor activator (C.E.R.A.) is used for the treatment of anemia in adults…

A disease model for Multiple Myeloma developed using Real World Data and validated on Phase 3 clinical trials

Thursday 16 October, 2025

Objectives: Multiple myeloma (MM) is a neoplasm characterized by the proliferation and accumulation of malignant plasma cells. MM remains incurable…