Thursday 16 October, 2025
OrBiTo is a new European project within the IMI programme in the area of oral biopharmaceutics tools that includes world…
Read moreOral: Mechanistic Absorption Modelling
An in silico physiologically-based pharmacokinetic (PBPK) study of the impact of the drug release rate on oral absorption, gut wall metabolism and relative bioavailability
Thursday 16 October, 2025
Objectives: To investigate the impact of the drug release rate on oral drug absorption and CYP3A4-mediated gut wall metabolism and to…
Read moreMechanism-based modelling of gastric emptying and bile release in response to caloric intake
Thursday 16 October, 2025
Objectives: We aimed to establish a mechanism-based model for gastric emptying (GE), cholecystokinin (CCK) plasma concentrations and gallbladder (GB) emptying in…
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