Thursday 16 October, 2025
This tutorial will cover the integration of advanced data analytics, specifically Artificial Intelligence (AI) and Machine Learning (ML), into model-informed…
Read moreOral: Keynote lecture
Current and future applications of circulating tumor DNA (ctDNA) to oncology drug development
Thursday 16 October, 2025
Objectives: The objectives of the presentation are Describe the assays used to measure ctDNA. Discuss the applications of ctDNA in…
Read moreModeling biology by agents
Thursday 16 October, 2025
Objectives: We describe the agent-based modelling methodology for simulating complex biological phenomena. Overview/Description of presentation: The agent-based modelling (ABM) paradigm is…
Read moreAdaptive trial designs: opportunities and challenges
Thursday 16 October, 2025
The use of adaptive designs can increase the efficiency of drug development by improving our ability to efficiently learn about…
Read morePre-clinical and clinical applications of PBPK models for monoclonal antibodies and other large molecule modalities.
Thursday 16 October, 2025
Physiologically based pharmacokinetic (PBPK) models for large molecules combine information on the biological system together with information specific to the…
Read morePharmacometrics to support clinical investigation during COVID-19 pandemics : a viral dynamics perspective
Thursday 16 October, 2025
Objectives: We will present our involvement into the design and the analysis of clinical trials, and how we used pharmacometrics…
Read moreTutorial on application of survival analysis to the assessment of multiple state models in clinical data analysis.
Thursday 16 October, 2025
Objectives: Application of survival analysis methods to competing risks, multistate models and patient benefit. . Methods: If a clinical trial…
Read moreModeling and Simulation of SARS-CoV-2 Infections, Hospitalizations and Outcome in Germany
Thursday 16 October, 2025
The COVID-19 pandemic challenged many national health care systems with hospitals reaching capacity limits of intensive care units (ICU). Hence,…
Read moreTutorial on survival analysis and its application to the assessment of competing risks in clinical data analysis.
Thursday 16 October, 2025
Objectives: Theory of survival analysis. Application to competing risks, multistate models and patient benefit. Overview/Description of presentation: Part 1: Fundamentals….
Read morePharmacometrics to support clinical investigation during COVID-19 pandemics
Thursday 16 October, 2025
Objectives: We will present our involvement into the design and the analysis of clinical trials, and how we used pharmacometrics…
Read more