Thursday 16 October, 2025
Overview/Description of presentation: The concept of harnessing the immune system to fight cancer is not new, but only recently have…
Read moreOral: Immunotherapy in oncology
Predicting response and identifying responders to combination cancer immunotherapy in melanoma using Quantitative Systems Pharmacology (QSP) models
Thursday 16 October, 2025
Introduction: QSP models at various levels of physiological detail can support decision making in various stages of the cancer immunotherapy…
Read moreDrug response variability and optimal dosing in immuno-oncology
Thursday 16 October, 2025
Objectives: Present some aspect of the biology and mechanistic PK/PD modelling, including clear applications in the early clinical space driving…
Read morePKPD analysis of soluble CD25 to characterize the concentration-effect relationship observed following the administration of Cergutuzumab Amunaleukin, a targeted immunocytokine for cancer immunotherapy
Thursday 16 October, 2025
Objectives: 1. To quantify the concentration-effect relationship of Cergutuzumab Amunaleukin (CA) on the plasma pharmacodynamics (PD) marker soluble CD25 (sCD25),…
Read more