Abstracts - PAGE Meeting (Population Approach Group Europe)

Abstracts (30)

I-012Guiva Annane

ß-lactams Antibiotics in Obese Adults: A Review of Population Pharmacokinetic Analyses

Wednesday 10:30-12:00

I-026Luca Barberi

Replacing transit compartments with the analytical solution of a partial differential equation in malaria liver-stage modeling

Wednesday 10:30-12:00

I-031Stella Belin

The Challenges of Reproducible Computations in Pharmacometrics: Best Practices and Solutions

Wednesday 10:30-12:00

I-057Jonathan Chauvin

Automated concentration-QT data preparation, model selection and reporting in R

Wednesday 10:30-12:00

I-080Kseniia Danichkina

Survival data extraction: the comparison of methods, risk proportionality and informative censoring

Wednesday 10:30-12:00

I-085Dr. Amparo de la Peña

Improvements in Data Quality Can Boost Efficiency and Reduce Development Costs: Findings from a Survey of Pharmacometric CROs

Wednesday 10:30-12:00

I-106Jacob Dumbleton

reportifyr: an R-based Open-Source Tool for Automated Reporting

Wednesday 10:30-12:00

II-025Grace Shalom Govere

The use of modeling and simulation to inform Haemoglobinopathies drug development– a review of Scientific Advices from January 2014 to December 2024

Wednesday 15:30-17:00

II-036Helene Haguet

Use of modeling and simulation to inform the development of monoclonal antibodies to treat moderate-to-severe asthma: a review of EMA centralized procedure from 2014 to 2024.

Wednesday 15:30-17:00

II-044Anneke Himstedt

Integrated human PK predictions: Beyond single parameters towards full profile benchmarking

Wednesday 15:30-17:00

II-048Zhe Huang

A review of population pharmacokinetic/pharmacodynamic and exposure response modelling in three clinical pharmacology journals (2023-2025)

Wednesday 15:30-17:00

II-070Aida Kawuma

Utilizing Typst and Quarto for Efficient Reporting in Pharmacometrics

Wednesday 15:30-17:00

II-103Diane Lefaudeux

High-Throughput PBPK Framework in R using Open Systems Pharmacology Software for Anti-Tuberculosis Drug Development

Wednesday 15:30-17:00

III-011Nicolas Luyckx

Sampling of parameter uncertainty in Campsis

Thursday 9:50-11:45

III-016Panos Macheras

Uncovering the true meaning of Cmax and [AUC]0-8: The end of a 72-year-long misconception

Thursday 9:50-11:45

III-027Kazuki Matsuda

Exploring Parameter Estimation When Applying Target-Mediated Drug Disposition Model with Drug Concentration Data Only

Thursday 9:50-11:45

III-035Anna Mishina

RECORD: software tool for streamlining documentation and enhancing communication of modeling analyses

Thursday 9:50-11:45

III-037Venelin Mitov

MMVSola: An Early PK/PD and Dose Predicting Tool for Antimalarial Drug Development

Thursday 9:50-11:45

III-050Martine Neyens

Interactive shiny application to support design of non-inferiority trials based on surrogate biomarkers.

Thursday 9:50-11:45

III-064David Outland

Towards a mechanistic basis of a dynamical vertex model of vascular endothelial cell morphology changes in response to wall shear stress

Thursday 9:50-11:45

III-099Anne Ravix

Exploring Bayesian TDM: a simulation-based proof of concept study for vancomycin dosing in virtual neonates

Thursday 9:50-11:45

III-110Daniel Roeshammar

A prostate cancer QSP framework to explore the efficacy and safety of novel immunotherapies on the InSilicoTrials simulation platform

Thursday 9:50-11:45

III-112Ine Skottheim Rusten

Operationalizing the ERAMET Digital Research Environment (DRE) – Building the Ecosystem

Thursday 9:50-11:45

IV-013Stephan Schaller

Development of an End-to-End Quantitative Model-Informed Drug Development (MIDD) Ecosystem

Thursday 15:00-16:45

IV-039Alaric Taylor-roffey

Thursday 15:00-16:45

IV-054Martin Umpierrez

preDose: An R-Package for Robust External Evaluation of PopPKPD Models Prior to Implementation in Real-Time MIPD

Thursday 15:00-16:45

IV-055Parth J. Upadhyay

An r Shiny application for the projection of dose ranges in preclinical and first in human clinical studies during the early stages of drug development

Thursday 15:00-16:45

IV-076Vo Thanh

Effective Dosage Regimens Selection Based-on PK/PD Targets within Simcyp Framework

Thursday 15:00-16:45

IV-099Liang Yang

Impacts of different aggregation methods and dropout types on MBMA models

Thursday 15:00-16:45

IV-102Dr Kenta Yoshida

BayesERtools: R package for exposure-response analysis with Bayesian approaches

Thursday 15:00-16:45