30th PAGE Meeting

Ljubljana - Slovenia
28 June - 1 July, 2022

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Abstracts (20)

I-01João Abrantes

ADaMO: End-to-end automation of Pharmacometric modelling in drug development, from dataset building to output generation

Wednesday 09:45-11:15

I-02Nicolas Azzopardi

Mechanistic model of contrast-enhanced ultrasound in colorectal cancer metastasis.

Wednesday 09:45-11:15

I-03Freya Bachmann

Computing Optimal Drug Dosing with OptiDose: Implementation in NONMEM

Wednesday 09:45-11:15

I-10Chao Chen

The area under the effect curve as a preclinical-to-clinical translation tool for predicting therapeutic dose of anti-infectives

Wednesday 09:45-11:15

I-11Henrik Cordes

Species-specific Expression Databases for Physiologically Based Pharmacokinetic Modeling

Wednesday 09:45-11:15

I-20Mélanie Guhl

Computation of standard errors at finite distance in non linear mixed effects models

Wednesday 09:45-11:15

I-24Laura Iavarone

Application of the Area Under the Effect Curve as in vivo efficacy driver in Visceral Leishmaniasis

Wednesday 09:45-11:15

I-25Woojin Jung

Containerized NONMEM and its assistant software in R development environment

Wednesday 09:45-11:15

I-28Silvia Maria Lavezzi

Translational pharmacology benchmarking of a novel drug candidate for an autoimmune disease

Wednesday 09:45-11:15

I-32Nicolas Luyckx

Campsis: A generic, easy-to-use and intuitive PK/PD simulation platform based on R packages RxODE and mrgsolve

Wednesday 09:45-11:15

I-35Frano Mihaljevic

Development of a level A in vitro/in vivo correlation (IVIVC) using applications of the MonolixSuite

Wednesday 09:45-11:15

I-39Marije Otto

Application of Item Response Theory in Early Phase Clinical Trials: Utilization of a Reference Model to Analyse the Montgomery-Åsberg Depression Rating Scale.

Wednesday 09:45-11:15

I-40Theodoros Papathanasiou

PKPD Exploratory Graphics (xGx) Cheat Sheet

Wednesday 09:45-11:15

I-44Thao Nguyen Pham

Combining aggregate data and individual patient/subject data in model-based meta-analysis: An illustrative case study of tofacitinib in rheumatoid arthritis patients

Wednesday 09:45-11:15

I-48Christelle Rodrigues

Using preclinical data to predict human pharmacokinetics of monoclonal antibodies for first-in-human dose setting: A review of five internal case studies

Wednesday 09:45-11:15

I-51Sergio Sánchez Herrero

Ground-breaking software for modelling, simulation, optimization, estimation and validation applications in drug development timeline processes.

Wednesday 09:45-11:15

I-58Pauline Traynard

Validation of non-compartmental analysis (NCA) and bioequivalence results of PKanalix with respect to Phoenix WinNonLin and SAS.

Wednesday 09:45-11:15

I-59carla troisi

Population pharmacokinetics of continuous infusion ampicillin in the treatment of enterococcal infections in adult hospitalised patients

Wednesday 09:45-11:15

I-60Monika Twarogowska

A library of parent-metabolite models for the MonolixSuite

Wednesday 09:45-11:15

I-62Marinda van de Kreeke

Identifiability of drug effects in turn-over models with increasing complexity

Wednesday 09:45-11:15