Abstracts - PAGE Meeting (Population Approach Group Europe)

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Abstracts (32)

I-13Mike K Smith

Implementing “best practice” in Pop PK modeling

Wednesday 10:10-11:40

I-14Tom Snowden

A comparison of two model reduction methodologies for a QSP bone biology system with denosumab dosing.

Wednesday 10:10-11:40

I-16Eunjung Song

Bayesian estimation of parameters in the pharmacokinetic model

Wednesday 10:10-11:40

I-19Andrew Stein

Guiding dose selection of monoclonal antibodies using a new parameter (AFTIR) for characterizing ligand binding systems

Wednesday 10:10-11:40

I-22Claudia Suenderhauf

The Basel Phenotyping Capsule as a tool for Quantifying Human metabolism in vivo – a tool to personalize physiological and semiphysiological Models

Wednesday 10:10-11:40

I-29Nadia Terranova

The CICIL tool: a Java-based user-friendly application for the analysis of individual tumor size lesion dynamics

Wednesday 10:10-11:40

I-35Elena Tosca

In vitro-in vivo correlation (IVIVC) population modeling for the in silico bioequivalence of a long-acting release formulation of Progesterone.

Wednesday 10:10-11:40

I-48Marc Vandemeulebroecke

Graphical Principles Cheat Sheet

Wednesday 10:10-11:40

I-72Fan Zhang

Structural and Practical Considerations in the Development of a Parent-metabolite Model

Wednesday 10:10-11:40

I-73

Population pharmacokinetic/pharmacodynamic modeling of plasma lyso-sphingomyelin response to enzyme replacement therapy olipudase alfa in patients with acid sphingomyelinase deficiency

Wednesday 10:10-11:40

I-76Meng Zhaoling

Real World Evidence and Model-informed Drug Development – an antidiabetic drug cardiovascular outcome case study

Wednesday 10:10-11:40

II-13Thomas Frank

LaTeX-based report writing: 10 years’ experience from Sanofi’s M&S group in Germany

Wednesday 15:50-17:20

II-14Sebastian Frechen

A technical concept of automatic PBPK platform (re-)qualification in the Open Systems Pharmacology Suite (PK-Sim® and MoBi®)

Wednesday 15:50-17:20

II-28Nathalie Gobeau

Model-based informed screening of antimalarial combinations

Wednesday 15:50-17:20

II-31Ignacio Gonzalez-Garcia

Exploration of different scenarios using a drug exposure-response model of Lurbinectedin

Wednesday 15:50-17:20

II-34Sebastiaan Goulooze

Supervised item response theory modelling improves prediction of iatrogenic withdrawal in children

Wednesday 15:50-17:20

II-44Richard Hooijmaijers

ShinyMixR: A project-centric R/Shiny run management tool for nlmixr

Wednesday 15:50-17:20

II-45Andrew Hooker

Computation of the geometric mean and variance of the AUC using polynomial chaos

Wednesday 15:50-17:20

II-48Hwi-yeol Yun

Accurate and Precise Prediction of in-vivo hepatic clearance for drug with low KM

Wednesday 15:50-17:20

II-75Wojciech Krzyzanski

Implementation of delay differential equations in NONMEM

Wednesday 15:50-17:20

III-02Nada Abla Geiser

Development of PBPK drug models to support antimalarial combination strategy

Thursday 09:55-11:30

III-43Estelle Chasseloup

Generation and Application of Avatars (Digital Twins) in Pharmacometric Modelling

Thursday 09:55-11:30

III-51Jason Chittenden

PMDatR: A Pharmacometric Data Manipulation Package for R

Thursday 09:55-11:30

III-64Giuseppe De Nicolao

Analysis of muscular biopsy distributional data in Duchenne Muscular Dystrophy treatment: a population approach

Thursday 09:55-11:30

IV-20Paolo Magni

Evaluation of software tools for Bayesian estimation on population models: an update based on current software versions

Thursday 15:10-16:40

IV-22Victor Mangas-Sanjuan

Defining level A IVIVC dissolution specifications based on individual in vitro dissolution profiles

Thursday 15:10-16:40

IV-36Asbjørn Nøhr-Nielsen

A review of fixed-dose combination approvals in the EU based on European public assessment reports (EPARs)

Thursday 15:10-16:40

IV-37Patrick Nolain

PopkinR: a suite of Shiny applications focused on the pharmacometrics workflow

Thursday 15:10-16:40

IV-54

Using real world data to assess SGLT2 Inhibitor cardiovascular benefit and impacts of patient population characteristics

Thursday 15:10-16:40

IV-55Henning Schmidt

Reproducible submission-ready Word reports based on open source tools

Thursday 15:10-16:40

IV-67Hanne Refsgaard

Steps Towards a Robust Generic Method for Deconvolution Directly on Pharmacokinetic Profiles

Thursday 15:10-16:40

IV-74Oliver Sander

Detecting and Analyzing 5x Sit-to-Stand Tests from Accelerometer Data

Thursday 15:10-16:40