27th PAGE Meeting

Montreux - Switzerland
29 May - 1 June, 2018

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Abstracts (18)

I-02Johannes Schropp

Characterization of bispecific antibodies and the ternary complex including an optimal dosing strategy

Wednesday 10:10-11:40

I-42Piet van der Graaf

Systems pharmacology modelling of the alternative pathway to study target suitability

Wednesday 10:10-11:40

I-54Shijun Wang

A comparison between nonlinear mixed effects and naïve pooled data methods in population PK model selection

Wednesday 10:10-11:40

II-03Elvira Erhardt

Bayesian knowledge integration for an in vitro–in vivo correlation (IVIVC) model

Wednesday 15:50-17:20

II-26Eva Germovsek

An exposure-response model relating nicotine plasma concentration to momentary craving across different nicotine replacement therapy formulations

Wednesday 15:50-17:20

II-51Mohamed Ismail

An open source software solution for automating pharmacokinetic/pharmacodynamic model selection

Wednesday 15:50-17:20

II-56Jane Knöchel

Focusing on the essential dynamics of systems pharmacology models by exploiting an input-response characterisation

Wednesday 15:50-17:20

III-29

Characterization of anti-drug antibodies using a bivariate mixed hidden Markov model

Thursday 09:55-11:30

III-32Astrid Broeker

An integrated pharmacometric dialysis model to evaluate the pharmacokinetic impact of renal replacement therapy

Thursday 09:55-11:30

III-39Blesson Chacko

Covariate effects on competing events: a simulation study comparing approaches

Thursday 09:55-11:30

III-47Mohammed Cherkaoui Rbati

A Liver Model for Chemoprotection Against Malaria

Thursday 09:55-11:30

III-60Daniel Kaschek

An Integrated R-Based Framework for Model Development in Health Economics

Thursday 09:55-11:30

IV-05Robert Leary

Automatic framework for bioequivalence studies from In Vitro test to In Vivo study design

Thursday 15:10-16:40

IV-26Hannah Mayer

A novel approach to estimate ontogenies for PBPK applications – From literature data to simulations

Thursday 15:10-16:40

IV-28Nicola Melillo

Variance based Global Sensitivity Analysis of a Physiological Absorption model for compounds in different BCS classes

Thursday 15:10-16:40

IV-57Cesar Pichardo

QSP Modelling of Neurodegenerative Chronic Diseases and Brain Biomarkers: Adding the Effect of Ageing on Brain Volume

Thursday 15:10-16:40

IV-60Nikhil Pillai

Estimating parameters of chaotic systems: chaos synchronization combined with Nelder-Mead search

Thursday 15:10-16:40

IV-63Manuel Prado-Velasco

New approach based on physiological modelling to compute the bioavailability using the PhysPK biosimulation system

Thursday 15:10-16:40