26th PAGE Meeting

Budapest - Hungary
6-9 June, 2017

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Abstracts (15)

I-28Asuka Suzuki

A Bayesian approach for population pharmacokinetic modeling of alcohol in Japanese Subjects

Wednesday 10:30-12:00

I-31Ana Novakovic

A longitudinal model linking absolute lymphocyte count (ALC) and volume of T2 lesions to expanded disability status scale (EDSS) in patients with relapsing-remitting multiple sclerosis (RRMS)

Wednesday 10:30-12:00

I-46Jonás Samuel Pérez-Blanco

Population PK and exposure-response analysis of sleep parameters for JNJ-42847922, a novel Orexin 2 receptor antagonist

Wednesday 10:30-12:00

I-47Carlos Perez-Ruixo

Identifying lack of adherence to antipsychotic treatment using plasma concentrations measurements

Wednesday 10:30-12:00

I-55Angelica Quartino

Crenezumab exposure-response across Alzheimer’s Disease endpoints supports a higher dose for Phase 3

Wednesday 10:30-12:00

I-64Alberto Russu

Dose-conversion factors for risperidone and paliperidone formulations based on steady-state PK similarity

Wednesday 10:30-12:00

II-08Marina Senek

Population pharmacokinetic model for levodopa/carbidopa microtablets in Parkinson’s disease patients and healthy subjects

Wednesday 15:10-16:30

II-43Eline van Maanen

A systems pharmacology approach unravels the dynamics of the APP pathway and unfolds Aß oligomer modulation

Wednesday 15:10-16:30

III-14Francois Gaudreault

Circadian quantitative system pharmacology model to inform clinical study design and translation to human

Thursday 09:50-11:20

III-24Monia Guidi

Adequacy of open-loop Target Controlled Infusion devices during anesthesia

Thursday 09:50-11:20

III-41Jin Jin

Crenezumab exposure-response across Alzheimer’s Disease endpoints supports a higher dose for Phase 3

Thursday 09:50-11:20

III-44Siv Jonsson

Placebo and drug response assessment on Unified Parkinson’s Disease Rating Scale using longitudinal Item Response Modelling

Thursday 09:50-11:20

IV-07Muhammad Waqar Ashraf

A semi-mechanistic model to characterize the pharmacokinetics of orally administered S-Ketamine in healthy human subjects

Thursday 14:45-16:15

IV-21Souvik Bhattacharya

Longitudinal Parkinson’s Disease Progression Model using Item-Response-Theory Utilized to Predict Treatment Effect of Levodopa

Thursday 14:45-16:15

IV-52Olivier David

CNP520 Phase III dose selection support: Identifying the doses producing a desired reduction in CSF Aß-40

Thursday 14:45-16:15