Abstracts - PAGE Meeting (Population Approach Group Europe)

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Abstracts (27)

I-21Leonid Gibiansky

vc-MMAE antibody-drug conjugates: a unified model describes pharmacokinetics of eight different compounds

Wednesday 10:20-11:40

I-23Britta Goebel

Modeling & Simulation of Long-Term Body Weight Loss during Obesity Pharmacotherapy

Wednesday 10:20-11:40

I-27

Item Response Modeling to Leverage Data from Historical Parkinson’s Disease Trials while Integrating Data from a Newer Version of the Clinical Endpoint

Wednesday 10:20-11:40

I-29Sylvain Goutelle

A nonparametric, multiple-model approach to optimize initial dosing and attainment of a target exposure interval: application to busulfan in pediatrics

Wednesday 10:20-11:40

I-51Itziar Irurzun-Arana

Attractor analysis of Boolean models for Systems Pharmacology Networks

Wednesday 10:20-11:40

I-64Katrine Knøsgaard

A model-based approach for joint analysis of pain intensity and opioid consumption in postoperative pain

Wednesday 10:20-11:40

I-68Manish Kumar

Elucidating metabolic variations in gut microbiota during health and malnutrition based on genome scale metabolic modeling approach

Wednesday 10:20-11:40

II-10Yasunori Aoki

Model Averaging and Selection methods for model structure and parameter uncertainty quantification

Wednesday 15:10-16:30

II-19Levy Batista

Mixed-effects ARX model identification of dynamical systems

Wednesday 15:10-16:30

II-22Roberto Bizzotto

Mixed-effect deconvolution: a new method applied to oral paracetamol absorption

Wednesday 15:10-16:30

II-38Letizia Carrara

Methods and tools for multiscale modelling in Systems Pharmacology: a review

Wednesday 15:10-16:30

III-06Kurt Long

Identification of causal pathways determining the relationship between pathogen-specific infection and impaired growth among children < 59 months in Mirzapur, Bangladesh

Thursday 10:05-11:30

III-13Victor Mangas-Sanjuan

Exploring Inter-study variability in the context of modeling unperturbed xenograft data

Thursday 10:05-11:30

III-18

Modelling based methods to account for dropout in xenograft experiments

Thursday 10:05-11:30

III-41Stine Timmermann Ottesen

Analysing the contribution to receptor occupancy from active metabolites

Thursday 10:05-11:30

III-53Thomas Peyret

A mechanistic maternal-fetal growth energy budget model

Thursday 10:05-11:30

III-58Manuel Prado-Velasco

Bridging the gap between open and specialized modelling tools in PBPK/PK/PD with PhysPK/EcosimPro modelling system: PBPK model of methotrexate and 6-mercaptopurine in humans with focus in reusability and multilevel modelling features

Thursday 10:05-11:30

III-74Yue Ruan

Bayesian hierarchical model of glucose-insulin regulation over 12-week home use of closed-loop insulin delivery

Thursday 10:05-11:30

IV-06Johannes Schropp

Development and implementation of drug-drug interaction mechanisms with target-mediated drug disposition

Thursday 14:40-16:00

IV-07Partho Sen

Identification of foods with optimal nutritional value through data mining.

Thursday 14:40-16:00

IV-15

High-Resolution Image-based Computational Modeling of Breast Tumor Microvasculature

Thursday 14:40-16:00

IV-31Michel Tod

Comparison of the mechanistic static in vivo approach to a PBPK approach for prediction of metabolic drug-drug interactions.

Thursday 14:40-16:00

IV-41Vladimir Vainstein

Dose translation of a hematopoietic acute radiation syndrome protection agent (recombinant human Interleukin-12) to humans.

Thursday 14:40-16:00

IV-42Pyry Välitalo

A mathematical method assessing the informativeness of total test score on the basis of an item response theory model: A case study on pain in children

Thursday 14:40-16:00

IV-43Willem van den Brink

Finding underlying longitudinal patterns in pharmaco-metabolomics data

Thursday 14:40-16:00

IV-46Michiel Van Esdonk

Development of a semi-population deconvolution method for the analysis of growth hormone profiles

Thursday 14:40-16:00

IV-48

Competitive brain and body growth model

Thursday 14:40-16:00