Abstracts - PAGE Meeting (Population Approach Group Europe)

Abstracts (29)

I-01Thomas Dumortier

Using extrapolation to support a pediatric investigational plan: an application in liver transplantation development

Wednesday 10:20-11:40

I-14Aline Fuchs

Simulations to simplify gentamicin dosing regimens for neonates and young infants when referral is not possible in developing countries

Wednesday 10:20-11:40

I-18Eva Germovsek

Pharmacokinetic-pharmacodynamic (PKPD) modelling of meropenem in plasma and cerebrospinal fluid (CSF) in infants with late-onset sepsis and/or bacterial meningitis

Wednesday 10:20-11:40

I-26Verena Gotta

Characterizing age-dependency of cytokine levels in healthy children

Wednesday 10:20-11:40

I-55Carl Johansson

Omeprazole dose recommendation in pediatric patients aged 1-11 months with erosive esophagitis

Wednesday 10:20-11:40

I-72Jean Lavigne

Modeling and simulation of smear count after administration of Eurartesim® (piperaquine (PQ) tetraphosphate/dihydroartemisinin (DHA)) in infected patients with Plasmodium falciparum malaria

Wednesday 10:20-11:40

II-17Charlotte Barker

Simultaneous modelling of antimicrobial pharmacokinetic data from birth to adolescence: using different penicillins to inform a common maturation function

Wednesday 15:10-16:30

II-21Andrzej Bienczak

Semi-physiological pharmacokinetic/pharmacogenetic model with circadian rhythm for the characterisation of nevirapine pharmacokinetics in African children.

Wednesday 15:10-16:30

II-29Agnieszka Borsuk-De Moor

Population pharmacokinetics of sufentanil after epidural and intravenous administration in children and infants

Wednesday 15:10-16:30

II-32Jantine Brussee

Predictive performance of a CRP and organ failure based pharmacokinetic model for midazolam in critically ill children across external datasets in neonates, children and adults

Wednesday 15:10-16:30

II-35Elisa Calvier

Allometric scaling of clearance in paediatrics: when does the magic of 0.75 fade?

Wednesday 15:10-16:30

II-47Hyewon Chung

Population pharmacokinetics of F-ara-A after fludarabine administration in pediatric hematopoietic stem cell transplantation patients

Wednesday 15:10-16:30

II-54Sinziana Cristea

Maturation of Glomerular Filtration throughout the paediatric age-range; a comparison of different functions

Wednesday 15:10-16:30

II-56Salvatore D'Agate

Optimisation of weight-banded dosing regimens of amoxicillin in neonates and young infants with sepsis

Wednesday 15:10-16:30

II-59Pieter De Cock

piperacillin-tazobactam pharmacokinetics in critically ill children: implications on adequate dosing regimens

Wednesday 15:10-16:30

II-64Brenda de Winter

Pharmacokinetics of Pentobarbital in Pediatric Status Epilepticus Patients

Wednesday 15:10-16:30

II-76Hélder Duarte

Amikacin in premature newborn: a new therapeutic proposal from a PopPK model

Wednesday 15:10-16:30

III-12Adedeji Majekodunmi

Mechanistic modelling of naive CD4+ T cell homeostasis in HIV-infected children on anti-retroviral therapy

Thursday 10:05-11:30

III-20Paolo Mazzei

Population exposure-response modeling of oral nepadutant administration in infants with colic

Thursday 10:05-11:30

III-28Samer Mouksassi

Primary microcephaly: do all roads lead to Rome?

Thursday 10:05-11:30

III-31Silke Gastine

Population Pharmacokinetics of Voriconazole in pediatric cancer patients – assessing new dosing strategies

Thursday 10:05-11:30

III-40Sean Oosterholt

Model-based extrapolation and dosing recommendation for raxibacumab in children from birth to <18 years of age

Thursday 10:05-11:30

III-45Sophie Peigné

Optimal design in the analysis of a clinical study in paediatric population

Thursday 10:05-11:30

III-60Claire Pressiat

Population pharmacokinetics of cotrimoxazole In West African HIV-infected children

Thursday 10:05-11:30

III-71Christelle Rodrigues

Population pharmacokinetics of oxcarbazepine and its 10-monohydroxy derivative in epileptic children

Thursday 10:05-11:30

IV-49Swantje Völler

Dose Recommendations for Recombinant Asparaginase in Children: A Population Pharmacokinetic Analysis

Thursday 14:40-16:00

IV-60Pawel Wiczling

A Bayesian approach for population pharmacokinetic modeling of dexmedetomidine during long-term infusion in critically ill pediatric patients.

Thursday 14:40-16:00

IV-62Jayson Wilbur

Zika microcephaly cutoffs revisited: A study of Non-parametric methods in fetal growth

Thursday 14:40-16:00

IV-63Julia Winkler

Population pharmacokinetics of lacosamide to support intravenous dose adaptation in children with epilepsy

Thursday 14:40-16:00