Abstracts - PAGE Meeting (Population Approach Group Europe)

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Abstracts (27)

I-09Floriane Lignet

Computational Model of In Vitro Breast Cancer Cells Spheroid-Formation

Wednesday 10:15-11:45

I-17Victor Mangas-Sanjuan

Three Compartment Model To Describe Atipical Permeability Profiles In CACO-2 Cells

Wednesday 10:15-11:45

I-30Samer Mouksassi

Equivalence of locally acting drugs based on pharmacodynamic data: development of a novel 1 step method and use of trial simulations to assess sources of variability and power definitive studies

Wednesday 10:15-11:45

I-39Yookhwan Noh

Bioequivalence evaluation using population modeling method

Wednesday 10:15-11:45

I-53Elodie Plan

Bayesian Joint Modeling of Bone Mineral Density and Repeated Time-To-Fracture Event for Multiscale Bone Systems Model Extension

Wednesday 10:15-11:45

I-63Rachel Rose

Prediction of the Hypnotic Effects of Zolpidem by Extrapolation of a Mechanism-Based PKPD Model Developed for Triazolam in Healthy Volunteers.

Wednesday 10:15-11:45

II-02Muhammad Waqas Sadiq

Oxymorphone PKPD relationship and blood-brain barrier transport studied with microdialysis

Wednesday 15:10-16:40

II-15Monica Simeoni

Estimation of Remifentanil Metabolic Ratio Using a Mixture Model

Wednesday 15:10-16:40

II-51Georgios Vlasakakis

Landscape on technical and conceptual requirements in Drug/Disease Modelling & Simulation

Wednesday 15:10-16:40

II-56Sebastian Weber

Mixed effect modeling of neuronal cell differentiation kinetics from longitudinal phase-contrast imaging data

Wednesday 15:10-16:40

III-05Claire Ambery

Application of population dose-response and dose frequency in respiratory

Thursday 10:05-11:35

III-15Margherita Bennetts

Delta Method Application: Landmark Prediction and Confidence Interval for a Non-Linear Longitudinal Model

Thursday 10:05-11:35

III-32Theresa Cain

A systems approach to predicting differences in pharmacological response to a CYP1A2 substrate, resulting from pharmacokinetic differences in non-smokers, passive smokers and heavy smokers

Thursday 10:05-11:35

III-36Pascal Chanu

On the use of hemodynamics biomarkers to assess the benefit of high doses of sildenafil in some patients with pulmonary arterial hypertension (PAH)

Thursday 10:05-11:35

III-38Chao Chen

Quantifying the Effectiveness of Dose Personalisation by Simulation for a Drug with Moderate Pharmacokinetic Variability

Thursday 10:05-11:35

III-39Marylore Chenel

In vitro – in vivo correlation by population approach applied to modified-release forms with double-peak absorption

Thursday 10:05-11:35

III-65Christine Falcoz

Population PKPD modeling of an anti-diabetic compound with a new mechanism of action in ob/ob mice to predict the human dose

Thursday 10:05-11:35

IV-02Ben Francis

Using Stochastic Control Methods and Pharmacokinetics to Individualise Drug Therapy: A Case Study with the Enzyme Inhibitor Imatinib.

Thursday 15:00-16:30

IV-03

Practical Implications of Ontology and Global Standards for Model-based Data Analysis

Thursday 15:00-16:30

IV-08Aline Fuchs

Benchmarking therapeutic drug monitoring software: A systematic evaluation of available computer tools

Thursday 15:00-16:30

IV-13Leonid Gibiansky

Monoclonal Antibody-Drug Conjugates (ADC): TMDD Equations, Approximations, and Identifiability of Model Parameters

Thursday 15:00-16:30

IV-18

Population Pharmacokinetics of Two Volatile Markers Used for Assessment of Definitive Adherence

Thursday 15:00-16:30

IV-22Navin Goyal

Kinetic-Pharmaco Dynamic (K-PD) Modeling of a Novel Oral 5-Lipoxigenase Activating Protein (FLAP) Inhibitor for Asthma and its Comparison with a PK-PD Approach

Thursday 15:00-16:30

IV-40An Hyungmi

The Modified Bland-Altman Method to Measure Agreement with Repeated Measures Data using Random Effects Model

Thursday 15:00-16:30

IV-52

Therapeutic drug monitoring : modeling to assess risk and benefit for a novel drug used in combination

Thursday 15:00-16:30

IV-62Wojciech Krzyzanski

Methods of Solving Rapid Binding Target-Mediated Drug Disposition Model for Two Drugs Competing for the Same Receptor

Thursday 15:00-16:30

IV-65

Application of a new method for multivariate analysis of longitudinal ordinal data testing robenacoxib in canine osteoarthritis

Thursday 15:00-16:30