20th PAGE Meeting

Athens - Greece
7-10 June, 2011

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Abstracts (20)

I-07Anders Kristoffersson

Optimal design of in vitro time kill curve experiments for the evaluation of antibiotic effects.

Wednesday 10:15-11:45

I-08

Trial Sample Size Estimation and Study Design Assessment using Monte Carlo Sampling

Wednesday 10:15-11:45

I-12Caroline Bazzoli

New features for population design evaluation and optimisation with R functions: PFIM Interface 3.1 and PFIM 3.2

Wednesday 10:15-11:45

I-34Núria Buil Bruna

The feasibility of model-based exposure calculations in preclinical toxicology

Wednesday 10:15-11:45

II-04

Evaluation of designs for biosimilarity crossover trials analysed by nonlinear mixed effects models

Wednesday 14:55-16:10

II-06

Design evaluation in nonlinear mixed effect models: influence of covariance between random effects

Wednesday 14:55-16:10

II-12Karl-Heinz Liesenfeld

Modeling and simulation to optimise the study design investigating the hemodialysis of dabigatran in patients with end stage renal disease (ESRD)

Wednesday 14:55-16:10

II-30Gordon Graham

An Application of Optimal Design to Dose Selection and Sample Size Determination with a Negative-Binomial Exposure-Response Model for a Phase IIb Study

Wednesday 14:55-16:10

II-54Matts Kågedal

Improved study design in phase IIb by the use of optimal design, focusing on the precision of dose finding

Wednesday 14:55-16:10

III-24France Mentré

Comparison of results of the different software for design evaluation in population pharmacokinetics and pharmacodynamics

Thursday 09:50-11:05

III-32Thu Thuy Nguyen

Evaluation of Fisher information matrix using Gaussian quadrature in nonlinear mixed effects models: application to dose-response trials

Thursday 09:50-11:05

III-33Thu Thuy Nguyen

Designing a dose-response study analysed by nonlinear mixed effects models

Thursday 09:50-11:05

III-38Joakim Nyberg

Parallelization in optimal experimental design using PopED

Thursday 09:50-11:05

III-39Joakim Nyberg

Population optimal design with correlation using Markov Models

Thursday 09:50-11:05

III-59Italo Poggesi

Efficiency criteria generated by optimal design tools should be evaluated in the light of study objectives

Thursday 09:50-11:05

III-64Elba Romero

PK/PD sampling design optimization following a sustained release formulation of triptorelin using optimal experimental design

Thursday 09:50-11:05

IV-20Amit Taneja

Optimisation of Screening Experiments for the Assessment of Analgesic Effects

Thursday 15:05-16:20

IV-24Donato Teutonico

Multivariate patient simulation for clinical trial optimization in COPD

Thursday 15:05-16:20

IV-43Camille Vong

Optimal Design of Anticancer Regimens

Thursday 15:05-16:20

IV-56Shuying Yang

Using Placebo FEV1 Response to Improve the efficiency of clinical trials in Asthma

Thursday 15:05-16:20