Abstracts - PAGE Meeting (Population Approach Group Europe)

Abstracts (7)

Daren Austin, Isabelle Pouliquen, Mark Baker

Use of mechanistic models to estimate target antigen load for monoclonal antibodies

Justin J Wilkins, Aurélie Gautier, Phil J Lowe

Bioequivalence, bootstrapping and case-deletion diagnostics in a biologic: a model-based analysis of the effect of formulation differences in a monoclonal antibody

E. Pigeolet (1), F. Luedicke (2), S. Balser (2), G. Pinault (1) and P. Lowe (1)

Granulocyte Colony Stimulating Factor Pharmacokinetics After Single and Repeated Administration of Several Doses.

Micha Levi (1), Nicolas Frey (2) , Susan Grange (2), Thasia Woodworth (3)

Relationship Between Serum Concentration of the Interleukin-6 Receptor Inhibitor, Tocilizumab (TCZ), and Disease Activity Score (DAS28) in Patients with Rheumatoid Arthritis

Maria C. Kjellsson(1), Kristin E. Karlsson(1), Andrew Hooker(1), Brigitte Lacroix(2), Maria Laura Sargentini-Maier(2), Armel Stockis(2), Mats O. Karlsson(1)

Exposure-response analysis of certolizumab pegol in Crohn’s disease population

Brigitte Lacroix(1,2), Mark Lovern(1), Armel Stockis(1), Maria Laura Sargentini-Maier(1), Mats O. Karlsson(2) and Lena E. Friberg(2)

Exposure-Response Modeling of the ACR20 Score in Rheumatoid Arthritis Patients Treated with Certolizumab Pegol.

D Ternant, A Aubourg, C Magdelaine-Beuzelin, D Degenne, H Watier, L Picon and G Paintaud.

Development of anti-infliximab antibodies increases infliximab clearance in inflammatory bowel diseases